“…2). However, this general suppression of Na+ influx by Ca2+ does not apply to K4 influx, which from low K+ concentrations is strongly promoted by Ca24 in washed tissue (9). Evidently, Ca2+ is effecting the Na4/K+ discrimination reported long ago by Epstein (10) and Jacobson et al (14) in which Ca2+ suppresses Na4 uptake at the same time as it promotes K+ uptake.…”