Reactions of Connective Tissue to Amalgam, Intermediate Restorative Material, Mineral Trioxide Aggregate, and Mineral Trioxide Aggregate Mixed With Chlorhexidine

Sümer, Mahmut; Muğlalı, Mehtap; Bodrumlu, Emre; Güvenç, Tolga

doi:10.1016/j.joen.2006.05.012

Cited by 57 publications

(76 citation statements)

References 22 publications

(24 reference statements)

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“…7 Studies have shown that MTA mixed with CHX produces a biocompatible material -insofar as it created weak inflammatory responses characterized by the presence of a fibrous connective tissue capsule in the subcutaneous tissues of rats 8 -with enhanced antimicrobial activity. 9 Although MTA has many favorable properties that support its clinical use, there are also several drawbacks, e.g., it is a material of difficult manipulation.…”

Section: Declaration Of Interestsmentioning

confidence: 99%

“…23 Moreover, it has been shown that the association between a mixture of MTA and 0.12% CHX has biocompatible effects when implanted subcutaneously in rats. 8 It is important to point out that, in the present study, CHX powder was added to the material instead of CHX solution or gel, in order to avoid the interference of vehicles normally associated with CHX, such as NATROSOL.…”

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confidence: 99%

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Influence of 2% chlorhexidine on pH, calcium release and setting time of a resinous MTA-based root-end filling material

et al. 2015

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The addition of chlorhexidine (CHX) to a resinous experimental Mineral Trioxide Aggregate (E-MTA) based root-end filling material is an alternative to boost its antimicrobial activity. However, the influence of chlorhexidine on the properties of this material is unclear. The aim of this study was to evaluate the influence of 2% chlorhexidine on the pH, calcium ion release and setting time of a Bisphenol A Ethoxylate Dimethacrylate/Mineral Trioxide Aggregate (Bis-EMA/MTA) based dual-cure experimental root-end filling material (E-MTA), in comparison with E-MTA without the addition of CHX and with conventional white MTA (W-MTA). The materials were placed in polyethylene tubes, and immersed in deionized water to determine pH (digital pH meter) and calcium ion release (atomic absorption spectrometry technique). The setting time of each material was analyzed using Gilmore needles. The data were statistically analyzed at a significance level of 5%. E-MTA + CHX showed an alkaline pH in the 3 h period of evaluation, the alkalinity of which decreased but remained as such for 15 days. The pH of E-MTA + CHX was higher than the other two materials after 7 days, and lower after 30 days (p < 0.05). All of the materials were found to release calcium ions throughout the 30 days of the study. The addition of CHX increased the calcium ion release of E-MTA to levels statistically similar to W-MTA. E-MTA showed shorter initial and final setting time, compared with W-MTA (p < 0.05). The addition of 2% CHX to MTA prevented setting of the material. The addition of CHX to E-MTA increased its pH and calcium ion release. However, it also prevented setting of the material.

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Section: Declaration Of Interestsmentioning

confidence: 99%

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confidence: 99%

Influence of 2% chlorhexidine on pH, calcium release and setting time of a resinous MTA-based root-end filling material

et al. 2015

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“…Mahmut Sumer (2006) 20 in their histopathological study have reported that MTA mixed with CHX materials were surrounded by fibrous connective tissue, indicating that they were well tolerated by the tissues, therefore, MTA/CHX seemed to be biocompatible when examined. Thus, in the present study, CHX was incorporated to enhance the antimicrobial effect of WMTA.…”

Section: Discussionmentioning

confidence: 99%

Effect of Two Different Hydrating Solutions on Antibacterial Property of White Mineral Trioxide Aggregate Against Enterococcus Faecalis - An in Vitrocomparative Study

Babu¹

2017

IOSR JDMS

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“…It appears that material choices, such as zinc phosphate cement, 5 amalgam, 5 zinc oxide eugenol cements, 6 polycarbonate cements, 7 glass ionomer cements, [8][9][10][11] resin adhesives [12][13][14] and cyanoacrylates 15 do not lead to predictable success for the treatment of exposed pulps. Outcomes with calcium hydroxide were superior but unpredictable for carious pulp exposures.…”

Section: Introductionmentioning

confidence: 99%

Pulp Capping with Mineral Trioxide Aggregate (MTA): A Retrospective Analysis of Carious Pulp Exposures Treated by Undergraduate Dental Students

Miles¹,

Gluskin²,

Chambers³

et al. 2010

Operative Dentistry

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©Operative Dentistry, 2010, 35-1, 20-28 JP Miles • AH Gluskin D Chambers • OA Peters Clinical RelevanceCarious pulp exposures present a therapeutic challenge for clinicians. Mineral trioxide aggregate (MTA) is a treatment option that may provide successful outcomes for the capping of carious pulp exposures in adult patients. However, the success measured as pulp survival over a period of one and two years of pulp caps performed by undergraduate dental students may be low. This study provides data regarding the impact of exposure sizes and other pre-operative variables on outcomes of MTA pulp caps in adults. SUMMARYThe current study estimated pulpal vitality after MTA pulp caps were performed by undergraduate student clinicians. At recall after 12 to 27 months, 51 pulp caps were clinically and radiographically assessed. Kaplan-Meier analyses were used to estimate overall success at 12 and 24 months, determined as the presence of a vital pulp, as well as impact of preoperative variables on pulp vitality at recall. Overall, one-year pulp survival was 67.7%, while the two-year survival rate was 56.2%. Tarone-Ware statistics indicated that neither age of the patient nor size of the exposure ("minimal" or "moderate") and the amount of bleeding ("none," "minimal" or "moderate") had a significant effect on survival rates.Within the limitations of the current study on procedures performed by student clinicians, it may be concluded that, for MTA pulp caps applied to carious exposures in adults, certain preoperative conditions-patient age, exposure size and amount of bleeding-are not predictive of clinical outcome. Considering the comparatively low success rate for the current cohort, more research is needed to define predictive criteria for successful pulp capping with MTA.

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Reactions of Connective Tissue to Amalgam, Intermediate Restorative Material, Mineral Trioxide Aggregate, and Mineral Trioxide Aggregate Mixed With Chlorhexidine

Cited by 57 publications

References 22 publications

Influence of 2% chlorhexidine on pH, calcium release and setting time of a resinous MTA-based root-end filling material

Influence of 2% chlorhexidine on pH, calcium release and setting time of a resinous MTA-based root-end filling material

Effect of Two Different Hydrating Solutions on Antibacterial Property of White Mineral Trioxide Aggregate Against Enterococcus Faecalis - An in Vitrocomparative Study

Pulp Capping with Mineral Trioxide Aggregate (MTA): A Retrospective Analysis of Carious Pulp Exposures Treated by Undergraduate Dental Students

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