Reactions of Bis-dithiophosphonic Acids with 3-Hydroxypyridine and 3-(Hydroxymethyl)pyridine

3-Hydroxypyridine and 3-(Hydroxymethyl)pyridine in the Synthesis of Salts of Aryldithiophosphonic Acids on the Basis of Monoterpenyl Alcohols

“…The use of phosphorus dithioacids in the reactions with pyridine alkaloids is likely to lead to low toxicity organosulfurphosphorus derivatives possessing ionic structures and promising as antimicrobials. Thus, the antimicrobial activity of pyridinium salts of dithiophosphoric acids on the basis of 3hydroxypyridine and 3-pyridinemethanol, as well as the corresponding 3-hydroxypyridinium bisdithiophosphonic acids, was recently established (13,14). In the development of research on synthesis of antimicrobial pyridinium salts of phosphorus dithioacids, we turned to chiral dithiophosphonic acids on the basis of optically active monoterpenyl alcohols as well as racemic and aryl monoterpenyl alcohols.…”