Reactions of 4,5-diaminopyrazoles with chalcones and acetylarenes

Preparation of some light-sensitive 2-nitrophenyl-2,3-dihydro-1H-benzodiazepines

“…[1][2][3][4][5][6][7][8][9][10][11][12][13] An alternative synthesis employs an acetophenone derivative and a 1,2-diamine (2:1 equivalents ratio) in acidic medium. 3,4,6 Benzodiazepines are important compounds because of various biological activities. [13][14][15] It is known that benzodiazepines affect the CNS, and some 2,4-diaryl-7,8-dimethyl-2,3-dihydro-1H-1,5-benzodiazepines have been tested against breast cancer and have shown moderate activity.…”

Synthesis of 1-Benzyl-6-(4-chlorophenyl)-2-(4-R-phenyl)-4-(4-Rstyryl)-2,3-dihydropyrazolo[3,4-b][1,4]diazepines

“…The main feature of their mass spectra is that the base peak is also the molecular ion. It is important to observe that the orientation in this cycloaddition is the same as that discussed in our previous work [ 8 , 9 , 10 , 11 ], where it was shown that the azomethine bond on the seven-member ring is formed with participation of the amino group at the 4-position on the pyrazole ring.…”

The Structure ofN‐phenyl‐pyrazoles and Indazoles: Mononitro, Dinitro, and Trinitro Derivatives

“…36 : torsion = 33.0°; N1 = 110.8°, N2 = 105.6°, Δθ = 5.2°. 37 : torsion = 29.9°; N1 = 112.1°, N2 = 104.6°, Δθ = 7.5°. 38 : torsion = 7.2°; N1 = 112.7°, N2 = 105.1°, Δθ = 7.6°.…”