Reaction-Triggered ESIPT Active Water-Soluble Polymeric Probe for Potential Detection of Hg²⁺/CH₃Hg⁺ in Both Environmental and Biological Systems

Abstract

Mercury (Hg 2+ )-triggered desulfurization of 1,3dithiolane to the formyl group formation process has been utilized here to develop a norbornene-based reaction-triggered ESIPT active probe (NT). Mercury (Hg 2+ ) activated the excited-state proton transfer (ESIPT) process of both NT and its water-soluble polymer Poly-PEG-NT to change the emission from colorless to cyan-green. Due to the Hg 2+ -sensitive reaction site, NT and Poly-PEG-NT serve as highly selective and ultrafast detection systems with a limit of detection (LOD) of 8.2 nM and 107 nM, respectively. Additionally, NT can detect the organic mercury species (CH 3 Hg + ) with a quick response time and an impressive LOD of 1.1 μM. Due to the water-soluble nature of Poly-PEG-NT, it has the capability of detecting Hg 2+ in pure aqueous meda. Both these probes are capable of detecting Hg 2+ in both environmental and biological systems with excellent efficiency. Overall, the easy synthesis, cost-effectiveness, ultrafast detection, high selectivity, and sensitivity of NT and Poly-PEG-NT toward Hg 2+ /CH 3 Hg + can be used for practical purposes with efficiency to counter mercury toxicity.

Engineering a bromophenol derivative for rapid detection of Hg2+/CH3Hg+ in both environmental and biological samples through a unique activation process

“…Therefore, a similar reaction process is also expected for CH 3 Hg + towards BDT to show the changes in emission properties, as we proved in our previous work. 46 This mechanism has been further supported by the ESI-MS study of BDT in the presence of Hg 2+ (Fig. S14, ESI†), where m / z = 227.195 represents the mass of BDA which confirms the desulfurization of BDT .…”

“…Therefore, a similar reaction process is also expected for CH 3 Hg + towards BDT to show the changes in emission properties, as we proved in our previous work. 46…”

Oxidized Bis(indolyl)methane Derivatives with Diverse Signaling Units: An Excitation-Dependent Fluorescence Response toward Heavy Metal Pollutants in an Aqueous Medium

“…Herein, we have synthesized two chromogenic probes with an oxidized bisindolyl scaffold. Recently, bis­(indolyl)­methane (BIM)-based chromogenic probes have gained enormous public attention due to their applications in diverse fields, such as fabrication of optoelectronic devices, drug delivery, optical sensing, designing of solar cells, etc . Interestingly, selective excitation of either monomer species or nanoaggregates is possible by choosing a proper excitation channel.…”

Bismuth-Based BiOBrxI1–x/Ti3C2 MXene Schottky Nanocomposites for Hg2+ Photoelectrochemical Sensors

“…Heavy metal ions are highly toxic substances, which are harmful to the environment and the human body. , Studies have shown that even at very low concentrations, Hg 2+ can have serious adverse effects on the brain, kidneys, central nervous system, and immune system . Therefore, it is of great significance to establish an efficient and simple Hg 2+ detection method.…”