Reaction to D-penicillamine in rheumatoid arthritis.

Abstract

We feel that Gram-stain examination and culture of the fluid is the best means of differentiating between infection of the peritoneurm and aseptic peritonitis, two conditions that require different management.-We are, etc.

Penicillamine in rheumatoid arthritis ‐ A 2 year retrospective study in 70 patients

“…Penicillamine now has an established place in the management of rheumatoid arthritis (RA) (Multicentre Trial Group, 1973; Day et al , 1974; Dixon et al 1975; Brit. med J. editorial, 1975).…”

“…Recent reports, reflecting wide international experience suggest the use of penicillamine in small doses, starting with 125–250 mg daily and increasing the dose monthly to about 750 mg daily. This cautious regime is reducing the incidence of side‐effects (Day and Golding, 1974; Hill and Hill, 1975; Dixon et al , 1975). This report outlines our experience with penicillamine therapy since 1973, and adds further data to earlier opinions concerning penicillamine toxicity.…”