Reaction of Styrene with Chlorine Dioxide

Логинова, И. В.; Chukicheva, I. Yu.; Кучин, А. В.

doi:10.1134/s1070363218040308

Cited by 4 publications

(1 citation statement)

References 19 publications

(20 reference statements)

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“…The resulting products were isolated in good to excellent yields (80–87%). This route stood out due to its mild reaction conditions and good efficiency, although it should be noted that TsNBr 2 is not readily accessed [ 147 , 148 ]. In 2017, Loginova et al reported a ClO 2 -mediated oxidative chlorination of styrene [ 149 ].…”

Section: Oxyhalogenation Of Hydrocarbonsmentioning

confidence: 99%

Synthetic Access to Aromatic α-Haloketones

et al. 2022

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α-Haloketones play an essential role in the synthesis of complex N-, S-, O-heterocycles; of which some exhibit a remarkable biological activity. Research further illustrated that α-bromo-, α-chloro-, and α-iodoketones are key precursors for blockbuster pharmacological compounds. Over the past twenty years, substantial advances have been made in the synthesis of these industrially relevant building blocks. Efforts have focused on rendering the synthetic protocols greener, more effective and versatile. In this survey, we summarised and thoroughly evaluated the progress of the field, established in the past two decades, in terms of generality, efficacy and sustainability.

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Section: Oxyhalogenation Of Hydrocarbonsmentioning

confidence: 99%

Synthetic Access to Aromatic α-Haloketones

et al. 2022

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CV‐driven Optimization: Cobalt‐Catalyzed Electrochemical Expedient Oxychlorination of Alkenes via ORR

Tian

Jia

et al. 2019

Adv Synth Catal

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Instead of screening reaction conditions by yield-based chemical trial-and-error, potential-based cyclic voltammetry was alternatively employed for optimization of electrochemical oxychlorination of alkenes. With this unconventional screening method, the catalyst system including catalysts, molar ratio of chloride sources and solvents were identified in a rational, time-and energy-efficient manner. The optimal catalytic system in combination with oxygen reduction reaction enabled broad substrate scopes for the desired transformation by taking advantages of persistent radical effect. UV-vis and CV titration experiments confirmed the in-situ formed catalytic species [CoCl 5 ]. Moreover, cyclic voltammetry was applied to obtain mechanistic insights in our reaction system.

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