Reaction of [In(NEt₂)₃]₂ with N(CH₂CH₂NSiMe₃H)₃: Synthesis and Characterization of New Azaindatranes and Azaindocane

Abstract

[In(NEt2)3]2 and N(CH2CH2NSiMe3H)3 react to yield monomeric azaindatrane 1, N(CH2CH2NSiMe3)3In, which is unstable without additional donor (e.g. pyridine), turning into dimeric azaindatrane 2, [N(CH2CH2NSiMe3)2(CH2CH2NH)In]2. An intermediate product of this transformation is oligomeric azaindocane 3, [N(CH2CH2NSiMe3)2In(CH2CH2NSiMe3)]3. The composition and structures of new compounds have been established by 1H and 13C NMR spectroscopy. The crystal structures of 1·Py, trans‐2, and 3 have been determined by X‐ray diffraction studies. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)

Synthesis, X-ray Diffraction Studies, and DFT Calculations on Hexacoordinated Germanium Derivatives: The Case of Germaspirobis(ocanes)

“…However, only few papers have dealt with their synthesis, − and the structures of only two compounds have been determined by single-crystal X-ray diffraction. ,, On the other hand, it is well-known that hypercoordinated group 14 elements derivatives display a wide range of biological activity, which makes them interesting for medicinal chemistry and pharmacology. ,, Thus, spirobis(ocanes) ( III ) may also be potentially useful as therapeutic agents. As a part of our program to investigate the structure and chemical behavior of hypercoordinated germanium molecules, especially germatranes and germocanes, and to compare the degree of strength of the transannular M←N interactions with those in the derivatives of other main group elements, ,− we present the synthesis of three novel 1,7,9,15-tetraoxa-4,12-diaza-8-germaspiro[7.7]pentadecanes, i.e., [RN(CH 2 CHR‘O) 2 ] 2 Ge ( 1 − 3 ), which are the derivatives of N -methyldiethanolamine ( 4 ), N -methyl- N -(2-hydroxy-2-phenylethyl)ethanolamine ( 5 ), and N -phenyldiethanolamine ( 6 ), respectively. The motivation in our work was to study structural changes in hypercoordinated germanium compounds arising from the replacement of substituents at the different positions of the ligand cage.…”

The transannular interaction germanium–nitrogen in germocanes: The influence of substituents

“…In continuation of our investigations in the chemistry of metallatranes [39][40][41][42][43][44] and metallocanes [28] we focused our efforts on the synthesis and characterization of germocanes bearing various substituents at the Ge and N atoms, as well as at the carbon atoms of ocane skeleton. It should be noted that the latter compounds with substituents at C atoms are almost unexplored to date.…”