Reaction of 2-cyano-3-(4-oxo-4H-chromen-3-yl)prop-2-enamide with some phosphorus reagents: synthesis of some novel diethyl phosphonates, 1,2,3-diazaphosphinanes, 1,2,3-thiazaphosphinine and 1,2-azaphospholes bearing a chromone ring

Deeper insights into the density functional theory of structural, optical, and photoelectrical properties using 5-[(4-oxo-4H-chromen-3-yl) methylidene]-4-oxo (thioxo)-6-thioxo-2-sulfido-1, 3, 2-diazaphosphinanes

“…On the other hand, chromone compounds are well-known natural and synthetic products that showed significant biological activities including antiallergic (Nohara et al 1985), antiangiogenic (Lee et al 2005), antirheumatic (Ukawa, et al 1985), antitumor (Huang et al 2009), neuroprotective (Larget et al 2000), HIV-inhibitory (Ungwitayatorn et al 2004), antimicrobial (Göker et al 2005), antioxidant (Pietta et al 2000), and anti-inflammatory (Mazzei et al 1999). Appropriately, it seems, by all accounts, to be exceedingly appealing to study the previously synthesized 1,2,3-diazaphosphinines bearing a chromone ring 1-4 of biological intrigue from a computational investigation point of view (Ali and Hassan 2018). It has been uncovered those compounds containing 1,3,2-diazaphosphinines structures display noteworthy biological properties, which have attracted many researchers' attention in chemical biology and medicinal chemistry.…”

Synthesis and In Vitro Antimicrobial Activity of Some Novel pyrido[3,2- f][1,2,4,3]thiadiazaphosphepinone Compounds, bearing a pyridine moiety

“…Under stirring conditions, compound 2 interacted with Lawesson's reagent in acetonitrile to yield just single product, 8- (3,4- (5). The reaction pathway was assumed to proceed via nucleophilic attack of the amino group on LR, followed by the addition of SH to the cyano group.…”

Reaction of 2‐Imino‐2H‐chromene‐3‐carboxamide with Phosphorus Isothiocyanates: First Synthesis of Novel Chromeno[2,3‐d]pyrimidinyl and Bis(chromeno[2,3‐d]pyrimidinyl)phosphines and Chromeno[2′,3′:4,5]pyrimido[2,1‐d][1,3,5,2]triazaphosphinine

“…In our recent article , we studied the chemical reactivity of 2‐imino‐2 H ‐chromene‐3‐carboxamide ( 1 ) toward some phosphorus sulfides, which led to the formation of 2‐sulfido‐2,3‐dihydro‐4 H ‐chromeno[2,3‐ d ][1,3,2]diazaphosphinines. Considering the aforementioned facts and our program research on the development of new heterocyclic organophosphorus compounds , we herein reported the synthesis of phosphorus‐containing compounds possessing multi‐heterocyclic rings via treatment of 2‐imino‐2 H ‐chromene‐3‐carboxamide ( 1 ) with some phenyl phosphorus isothiocyanate reagents.…”