Reaction-induced phase separation of bis(triethoxysilyl)ethane upon sol–gel polymerization in acidic conditions

Ambati, Jyothirmai; Rankin, Stephen E.

doi:10.1016/j.jcis.2011.06.064

Cited by 14 publications

(6 citation statements)

References 67 publications

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“…The use of Fourier transform infrared spectroscopy (FTIR) is widely used for examining the evolution of the silica frameworks through their functional groups in a sol-gel reaction system 6 7 8 9 , and xerogel characterisation 10 11 12 . However, FTIR analysis of aqueous silica sol-gel is seldom reported.…”

mentioning

confidence: 99%

Ternary Phase-Separation Investigation of Sol-Gel Derived Silica from Ethyl Silicate 40

Wang

Smart

et al. 2015

Sci Rep

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A ternary phase-separation investigation of the ethyl silicate 40 (ES40) sol-gel process was conducted using ethanol and water as the solvent and hydrolysing agent, respectively. This oligomeric silica precursor underwent various degrees of phase separation behaviour in solution during the sol-gel reactions as a function of temperature and H2O/Si ratios. The solution composition within the immiscible region of the ES40 phase-separated system shows that the hydrolysis and condensation reactions decreased with decreasing reaction temperature. A mesoporous structure was obtained at low temperature due to weak drying forces from slow solvent evaporation on one hand and formation of unreacted ES40 cages in the other, which reduced network shrinkage and produced larger pores. This was attributed to the concentration of the reactive sites around the phase-separated interface, which enhanced the condensation and crosslinking. Contrary to dense silica structures obtained from sol-gel reactions in the miscible region, higher microporosity was produced via a phase-separated sol-gel system by using high H2O/Si ratios. This tailoring process facilitated further condensation reactions and crosslinking of silica chains, which coupled with stiffening of the network, made it more resistant to compression and densification.

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confidence: 99%

Ternary Phase-Separation Investigation of Sol-Gel Derived Silica from Ethyl Silicate 40

Wang

Smart

et al. 2015

Sci Rep

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“…This reaction is independent of low pH or temperature steps and does not require ultraviolet exposure. The polymerization rate (or gelation time) was determined per manufacturer's instructions and based on published literature (Ambati and Rankin, 2011; Lee et al, 2004; Jin et al, 2012; He et al, 2000; Hudalla et al, 2008). This rate was recorded as the amount of time (in minutes) from the combination of materials to form a solid product as determined by inversion and indentation.…”

Section: Methodsmentioning

confidence: 99%

Hydrogel formulation determines cell fate of fetal and adult neural progenitor cells

et al. 2014

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Hydrogels provide a unique tool for neural tissue engineering. These materials can be customized for certain functions, i.e. to provide cell/drug delivery or act as a physical scaffold. Unfortunately, hydrogel complexities can negatively impact their biocompatibility, resulting in unintended consequences. These adverse effects may be combated with a better understanding of hydrogel chemical, physical, and mechanical properties, and how these properties affect encapsulated neural cells. We defined the polymerization and degradation rates and compressive moduli of 25 hydrogels formulated from different concentrations of hyaluronic acid (HA) and poly(ethylene glycol) (PEG). Changes in compressive modulus were driven primarily by the HA concentration. The in vitro biocompatibility of fetal-derived (fNPC) and adult-derived (aNPC) neural progenitor cells was dependent on hydrogel formulation. Acute survival of fNPC benefited from hydrogel encapsulation. NPC differentiation was divergent: fNPC differentiated into mostly glial cells, compared with neuronal differentiation of aNPC. Differentiation was influenced in part by the hydrogel mechanical properties. This study indicates that there can be a wide range of HA and PEG hydrogels compatible with NPC. Additionally, this is the first study comparing hydrogel encapsulation of NPC derived from different aged sources, with data suggesting that fNPC and aNPC respond dissimilarly within the same hydrogel formulation.

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“…FTIR is widely performed for qualitatively examining the evolution of the silica frameworks through their functional groups for a sol-gel reaction system (Lee et al, 1997;Riegel et al, 1998;Ambati and Rankin, 2011;Olguin et al, 2014) and xerogel characterization (Tripp andHair, 1995, Liu et al, 2014;Masuda et al, 2014). In addition to the chemical information that could be gained from other functional groups, the degree of silica condensation can be qualitatively and semi-quantitatively determined from FTIR analyses.…”

Section: Attenuated Total Reflection Fourier-transformed Infrared (Ftir)mentioning

confidence: 99%

Advanced Materials for Polymeric Ultrafiltration Membranes Fabrication and Modification

Muhamad¹,

Nazri²,

Lau³

et al. 2018

Advanced Materials for Membrane Fabrication and Modification

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This book contains information obtained from authentic and highly regarded sources. Reasonable efforts have been made to publish reliable data and information, but the author and publisher cannot assume responsibility for the validity of all materials or the consequences of their use. The authors and publishers have attempted to trace the copyright holders of all material reproduced in this publication and apologize to copyright holders if permission to publish in this form has not been obtained. If any copyright material has not been acknowledged please write and let us know so we may rectify in any future reprint.Except as permitted under U.S. Copyright Law, no part of this book may be reprinted, reproduced, transmitted, or utilized in any form by any electronic, mechanical, or other means, now known or hereafter invented, including photocopying, microfilming, and recording, or in any information storage or retrieval system, without written permission from the publishers.

show abstract

Reaction-induced phase separation of bis(triethoxysilyl)ethane upon sol–gel polymerization in acidic conditions

Cited by 14 publications

References 67 publications

Ternary Phase-Separation Investigation of Sol-Gel Derived Silica from Ethyl Silicate 40

Ternary Phase-Separation Investigation of Sol-Gel Derived Silica from Ethyl Silicate 40

Hydrogel formulation determines cell fate of fetal and adult neural progenitor cells

Advanced Materials for Polymeric Ultrafiltration Membranes Fabrication and Modification

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