Re(V) complexes with amino acids based on the ‘3+2’ approach

Synthesis and crystal structure of the first oxofree ‘3+3’ rhenium(V) complex

“…The origin of the perrhenate anion in 1 is probably due to the oxidation of a portion of the [ReO 2 (py) 4 ] + starting material during its reaction with H 2 L 3 . This phenomenon has been observed previously for both rhenium(V) [6] and technetium(V) [7].…”

Redox Behavior of Re(V)–Amino Acid Containing Complexes

“…The state of the art in this field recognizes the concept of a mixed ligand in either the "n + 1" or the "n + 2" proposal as a suitable approach. In these complexes, n coordination positions are occupied by one ligand, which provides a stable structure to the [Re V O] 3+ core (3), whereas the other ligand, also called a coligand, completes the coordination sphere. The physicochemical properties as well as the redox behavior of the resulting complex can be modified by changing the nature of the coligand (3)(4)(5).…”

“…The preparation and characterization of Re complexes with structure [ReO(dien-H)(aa)] + (dien-H = NH 2 CH 2 CH 2 NCH 2 CH 2 NH 2 ; aa = amino acid) have been reported in the recent literature (3). Crystal structures of these complexes show a deprotonated dien occupying three equatorial positions and a deprotonated amino acid coordinated through the amine and the carboxylate groups (3).…”

“…Crystal structures of these complexes show a deprotonated dien occupying three equatorial positions and a deprotonated amino acid coordinated through the amine and the carboxylate groups (3). An important feature of this spatial configuration is the location of the amino acid carboxylate, which occupies a position trans to the oxo group in the octahedral.…”

Voltammetric studies of the interaction between Re(V) complexes and proteins

“…[ReO 2 L 2 ]I (L ¼ en, dien, trien, tren) and [ReO(dien-H)(val)]I were prepared as previously reported [26,27]. Bovine serum albumin (BSA), 67,000 Da, fraction V, was purchased from Sigma (USA).…”