Re: Histologic Evidence of New Collagen Formulation Using Platelet Rich Plasma in Skin Rejuvenation: A Prospective Controlled Clinical Study: Authors' Reply

Abuaf, Özlem Karabudak; Yıldız, Hamza; Baloğlu, Hüseyi̇n; Bilgili, Memet Erşan; Şimşek, Hasan; Doğan, Bilal

doi:10.5021/ad.2018.30.1.111

Cited by 2 publications

(4 citation statements)

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“…Similarly, we noticed the late therapeutic effect in our study, as changes were not evident by OCT except 6 weeks after the last treatment session which could be explained by the fact that neocollagenesis and significant tightening are only evident late during proliferative and maturation phase and not during the early inflammatory phase of healing 3 …”

Section: Discussionsupporting

confidence: 71%

“…12 Similarly, we noticed the late therapeutic effect in our study, as changes were not evident by OCT except 6 weeks after the last treatment session which could be explained by the fact that neocollagenesis and significant tightening are only evident late during proliferative and maturation phase and not during the early inflammatory phase of healing. 3 A previous study found a highly significant average improvement in skin tightening and lifting of the lower face according to Fitzpatrick's wrinkle and elastosis scale after 3 sessions of fractional RF microneedling. Although they used noninsulated needles and mentioned that it was superior to insulated needles in heat generation, 13 we used insulated needles in our study due to their higher safety profile in the neck area especially in pigmented skin.…”

Section: Discussionmentioning

confidence: 95%

“…Platelet‐rich plasma has been known in esthetic medicine as a method for skin rejuvenation. Various growth factors and cytokines that facilitate extracellular matrix (ECM) accumulation and improve cell proliferation and differentiation are activated after injection into the target tissue 3 …”

Section: Introductionmentioning

confidence: 99%

“…Various growth factors and cytokines that facilitate extracellular matrix (ECM) accumulation and improve cell proliferation and differentiation are activated after injection into the target tissue. 3 The current study aimed to evaluate and compare the efficacy and safety of fractional radiofrequency microneedling monotherapy and in combination with autologous platelet-rich plasma in neck rejuvenation.…”

mentioning

confidence: 99%

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Comparison of the efficacy of Fractional Radiofrequency Microneedling alone and in combination with platelet‐rich plasma in neck rejuvenation: a clinical and optical coherence tomography study

Gawdat

Allam

Hegazy

et al. 2021

J of Cosmetic Dermatology

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Section: Discussionsupporting

confidence: 71%

Section: Discussionmentioning

confidence: 95%

Section: Introductionmentioning

confidence: 99%

mentioning

confidence: 99%

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Comparison of the efficacy of Fractional Radiofrequency Microneedling alone and in combination with platelet‐rich plasma in neck rejuvenation: a clinical and optical coherence tomography study

Gawdat

Allam

Hegazy

et al. 2021

J of Cosmetic Dermatology

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Autolougous platelet concentrates in esthetic medicine

Davies,

Miron

2024

Periodontology 2000

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This narrative review summarizes current knowledge on the use of autologous platelet concentrates (APCs) in esthetic medicine, with the goal of providing clinicians with reliable information for clinical practice. APCs contain platelets that release various growth factors with potential applications in facial and dermatologic treatments. This review examines several facial esthetic applications of APCs, including acne scarring, skin rejuvenation, melasma, vitiligo, stretchmarks, peri‐orbital rejuvenation, peri‐oral rejuvenation, hair regeneration and the volumizing effects of APC gels. A systematic review of literature databases (PubMed/MEDLINE) was conducted up to October 2023 to identify randomized controlled trials (RCTs) in the English language on APCs for facial rejuvenation and dermatology. A total of 96 articles were selected including those on platelet rich plasma (PRP), plasma‐rich in growth factors (PRGF), and platelet‐rich fibrin (PRF). Clinical recommendations gained from the reviews are provided. In summary, the use of APCs in facial esthetics is a promising yet relatively recent treatment approach. Overall, the majority of studies have focused on the use of PRP with positive outcomes. Only few studies have compared PRP versus PRF with all demonstrating superior outcomes using PRF. The existing studies have limitations including small sample sizes and lack of standardized assessment criteria. Future research should utilize well‐designed RCTs, incorporating appropriate controls, such as split‐face comparisons, and standardized protocols for APC usage, including optimal number of sessions, interval between sessions, and objective improvement scores. Nevertheless, the most recent formulations of platelet concentrates offer clinicians an ability to improve various clinical parameters and esthetic concerns.

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Re: Histologic Evidence of New Collagen Formulation Using Platelet Rich Plasma in Skin Rejuvenation: A Prospective Controlled Clinical Study: Authors' Reply

Cited by 2 publications

References 1 publication

Comparison of the efficacy of Fractional Radiofrequency Microneedling alone and in combination with platelet‐rich plasma in neck rejuvenation: a clinical and optical coherence tomography study

Comparison of the efficacy of Fractional Radiofrequency Microneedling alone and in combination with platelet‐rich plasma in neck rejuvenation: a clinical and optical coherence tomography study

Autolougous platelet concentrates in esthetic medicine

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