Re-Evaluation of 400 Crimean-Congo Hemorrhagic Fever Cases in an Endemic Area: Is Ribavirin Treatment Suitable?

Duygu, Fazılet; Turan, Kaya; Baysan, Pinar

doi:10.1089/vbz.2011.0694

Cited by 31 publications

(29 citation statements)

References 29 publications

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“…Greater consideration as to whether the CCHFV vaccine is more efficacious in females should be given. Although ribavirin is often administrated to CCHF patients, it is unclear if it has a beneficial effect (Keshtkar-Jahromi et al 2011;Duygu et al 2012). Anti-CCHFV immunoglobulin, from convalescent CCHF patients, has also been used, but as for ribavirin, studies addressing its efficacy for CCHF patients are lacking (Keshtkar-Jahromi et al 2011).…”

Section: Crimean-congo Hemorrhagic Fevermentioning

confidence: 99%

Sex and Gender Differences in Infection and Treatments for Infectious Diseases

Klein

Roberts

2015

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This book provides an overview of the underlying sex-based and hormone-based differences in immunity, wound healing and pharmacokinetics, while also exploring how pregnancy affects immunity. The second part of the book shows, for the first time in a single volume, the growing number of infectious diseases for which sex and gender differences are noted, identifies common as well as distinct mechanisms mediating these differences and illustrates how responses to treatments might differ between the sexes. The awareness that males and females differ in their response to specific pathogens as well as to treatments for infectious diseases may yield sex-specific personalized treatments. This book will be of interest to basic scientists and clinicians in the fields of microbiology, immunology and pharmacology. Individuals working in academia, government and industry will also benefit from the information presented

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Section: Crimean-congo Hemorrhagic Fevermentioning

confidence: 99%

Sex and Gender Differences in Infection and Treatments for Infectious Diseases

Klein

Roberts

2015

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“…Tokat ili ülkemizde KKKA'nın endemik olarak görüldüğü bir bölgedir. İlimizde yapılan bir çalışmada 400 olgu retrospektif olarak incelenmiş ve daha önce Kasım ayında ilimizde hiçbir KKKA olgusunun izlenmediği görülmüştür (15). Ancak 2011 yılı Aralık ayında Türkiye'de kış ayında görülen ilk KKKA vakası bildirilmiştir (16).…”

Section: İrdelemeunclassified

A Crimean-Congo Hemorrhagic Fever Case in an Endemic Region in November

Tavsan¹,

Duygu²,

Turan³

2014

Klimik Dergisi

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“…12 However, in another study carried out in a similar setting, the CFR was 2.9% with the use of early ribavirin. 3 The 5% fatality rate cannot be accepted as normal.…”

mentioning

confidence: 94%