RCT protocol for driving performance in people with Parkinson's using autonomous in-vehicle technologies

Classen, Sherrilene; Li, Yuan; Giang, Wayne C.W.; Winter, Sandra; Wei, Jiajun; Patel, Bhavana; Jeghers, Mary; Gibson, Beth; Rogers, Jerry D.; Ramirez‐Zamora, Adolfo

doi:10.1016/j.conctc.2022.100954

Cited by 3 publications

(2 citation statements)

References 40 publications

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“…As far as our knowledge goes, this study will be the rst randomized controlled trial to investigate the effect of a nightshade elimination diet on in ammatory and rheumatologic markers of rheumatoid arthritis patients. Making a protocol publicly available helps us document our work and also helps other investigators to lay the foundation of their studies based on our protocol (22). Publishing study protocols will also inform the scienti c community of the studies that are being conducted, which helps avoid duplication (22).…”

Section: Discussionmentioning

confidence: 99%

“…Making a protocol publicly available helps us document our work and also helps other investigators to lay the foundation of their studies based on our protocol (22). Publishing study protocols will also inform the scienti c community of the studies that are being conducted, which helps avoid duplication (22). After conducting this RCT, the effect of nightshades on RA patients will be clearer than before and the result may be useful for nutritionists and physicians to advise patients about dietary guidelines.…”

Section: Discussionmentioning

confidence: 99%

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The evaluation of nightshade elimination diet (NED) on inflammatory and rheumatologic markers of rheumatoid arthritis patients: study protocol for a randomized controlled trial

Golmohammadi,

Hosseinikia,

Sadeghi

et al. 2023

Preprint

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Background and objectives Rheumatoid arthritis (RA) is a chronic disease with the global prevalence rate of 1%. Some RA patients constantly complain about adverse effects they are experiencing after consumption of nightshades. These plants contain Solanine which can cause damage to the bones and joints. Considering the literature, no RCT has been conducted about nightshade effects on RA patients, this study aims to assess the impact of a nightshade elimination diet (NED) on inflammatory and rheumatologic markers of rheumatoid arthritis patients for the first time. Methods A single-blinded controlled trial will be conducted to evaluate the effect of a NED on 36 participants for 8 weeks (2 months). The patients will be equally divided in two intervention and placebo groups. Both groups will receive general anti-inflammatory dietary recommendations and the Intervention group will be undergone a NED during the study. Clinical symptoms will be determined using questionnaires. Moreover, blood samples will be collected from participants to measure desired indicators. Discussion To the best of our knowledge, this study will be the first RCT investigating the effect of NED on inflammatory and rheumatologic markers of rheumatoid arthritis patients. The possible results of this study could be useful for nutritionists and physicians in managing RA patients. Trial registration Iranian Registry of Clinical Trials (irct.ir) IRCT20230220057465N1. Registered on 8 April 2023.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

The evaluation of nightshade elimination diet (NED) on inflammatory and rheumatologic markers of rheumatoid arthritis patients: study protocol for a randomized controlled trial

Golmohammadi,

Hosseinikia,

Sadeghi

et al. 2023

Preprint

View full text Add to dashboard Cite

show abstract

The evaluation of nightshade elimination diet (NED) on inflammatory and rheumatologic markers of rheumatoid arthritis patients: study protocol for a randomized controlled trial

Golmohammadi,

Hosseinikia,

Sadeghi

et al. 2024

Trials

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Feasibility of automated in-vehicle technologies on volunteers’ driving performance

Classen

Winter

Wei

et al. 2022

TAD

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BACKGROUND: Automated in-vehicle technologies, specifically in-vehicle information systems (IVIS) and advanced driver assistance systems (ADAS), are increasingly common in today’s cars. Previous studies illustrate benefits of using IVIS and ADAS to improve safety, convenience, and comfort in healthy older drivers. However, research is sparse on the feasibility of such technologies for medically at-risk drivers, such as those with Parkinson’s disease (PD). OBJECTIVE: This study enrolled healthy volunteer drivers to examine the feasibility of the procedures and measures for evaluating the effects of IVIS and ADAS on their driving performance. METHODS: During this feasibility study researchers compared drives completed with and without support of IVIS and ADAS, as participants drove a 2019 Toyota Camry XLE. The test vehicle was equipped with IVIS, ADAS, cameras, a telematics system, and sensors. Participants drove the road course supervised by a Driver Rehabilitation Specialist (DRS). RESULTS: Overall study procedures and vehicle equipment were feasible and provided sufficient data collection for measuring the impact of IVIS and ADAS on driving performance. Data observation by the DRS combined with data captured from cameras and telematics, facilitated comparisons to increase data reliability and validity. CONCLUSIONS: Feasibility study findings informed a randomized clinical trial, examining the use of IVIS and ADAS technologies as an intervention to support drivers with Parkinson’s disease.

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RCT protocol for driving performance in people with Parkinson's using autonomous in-vehicle technologies

Cited by 3 publications

References 40 publications

The evaluation of nightshade elimination diet (NED) on inflammatory and rheumatologic markers of rheumatoid arthritis patients: study protocol for a randomized controlled trial

The evaluation of nightshade elimination diet (NED) on inflammatory and rheumatologic markers of rheumatoid arthritis patients: study protocol for a randomized controlled trial

The evaluation of nightshade elimination diet (NED) on inflammatory and rheumatologic markers of rheumatoid arthritis patients: study protocol for a randomized controlled trial

Feasibility of automated in-vehicle technologies on volunteers’ driving performance

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