RBM10 regulates LncRNA SNHG17 alternative splicing to suppress colorectal cancer invasion mechanism research
Linxia An,
Peng Chen,
Miao He
et al.
Abstract:Objective: To explore the role of RBM10 in colorectal cancer (CRC) and the regulatory mechanism of CRC invasion through alternative splicing (AS) of long non-coding RNA (lncRNA) SNHG17 by RBM10.
Methods: Samples were collected from sixty cases of CRC and their corresponding adjacent normal tissues. Immunohistochemistry and Western blot were performed to analyze the expression of RBM10. A Transwell invasion assay was conducted to evaluate the effect of RBM10 on the invasion of HCT116 cells, and a Western blot w… Show more
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