2023
DOI: 10.22541/au.167407899.94032949/v1
|View full text |Cite
Preprint
|
Sign up to set email alerts
|

RBCK1 promotes the stabilization of HBx by linear ubiquitination to drive the progression of HBV-associated hepatocellular carcinoma

Abstract: Background & Aims: Linear ubiquitin chain assembly complex (LUBAC) has been reported to participate in cancer progression, but its role in hepatocellular carcinoma (HCC) remains unknown. This study aimed to investigate the functions and potential tumorigenic mechanisms of LUBAC components in HBV-associated HCC. Methods: The expression of LUBAC components ( RBCK1, RNF31, and Sharpin) and Met1-linked ubiquitination (M1-Ubi) and their correlation with prognosis were detected. The biological functions of RBCK1… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1

Citation Types

0
0
0

Year Published

2024
2024
2024
2024

Publication Types

Select...
1

Relationship

0
1

Authors

Journals

citations
Cited by 1 publication
(1 citation statement)
references
References 34 publications
0
0
0
Order By: Relevance
“…It is difficult to promote the application in the active distribution network with complex grid structures and multi-branch lines. In addition, some researchers reduce the active power loss of the line through coordinated scheduling (Wang et al, 2020;Li et al, 2023). Wang et al (2023) proposed a day-ahead-day cooperative scheduling method for the active distribution network based on the optimal economic operation area.…”
Section: Introductionmentioning
confidence: 99%
“…It is difficult to promote the application in the active distribution network with complex grid structures and multi-branch lines. In addition, some researchers reduce the active power loss of the line through coordinated scheduling (Wang et al, 2020;Li et al, 2023). Wang et al (2023) proposed a day-ahead-day cooperative scheduling method for the active distribution network based on the optimal economic operation area.…”
Section: Introductionmentioning
confidence: 99%