Rationally designed in-chain porous metallo-polymeric microsphere: A highly efficient and regenerative scavenger for ultra-trace arsenic from water

Joshi, Vipin Chandra; Gupta, Ankit; Indurkar, Pankaj D.; Sharma, Saroj

doi:10.1016/j.cej.2022.138420

Cited by 12 publications

(2 citation statements)

References 71 publications

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“…Therefore, the obtained binding data were analyzed with Freundlich, Scatchard, Langmuir and Dubinin–Radushkevich isotherms respectively (Table S1). − Interestingly, unlike previous results, , the adsorption equilibrium data of HDFGFR4/CMMNPs fit the Langmuir model better with the highest correlation coefficient ( r 2 = 0.9828). While the adsorption equilibrium data of FGFR4/CMMNPs were better fitted with the Freundlich model in line with previous findings, which is a commonly used model to describe the adsorption properties of nonhomogeneous surfaces.…”

Section: Resultscontrasting

confidence: 66%

Genetically Engineered Cell Membrane-Coated Nanoparticles with High-Density Customized Membrane Receptor for High-Performance Drug Lead Discovery

Bu,

Wu,

Zhao

et al. 2023

ACS Appl. Mater. Interfaces

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Cell membrane coating strategies have been increasingly researched due to their unique capabilities of biomimicry and biointerfacing, which can mimic the functionality of the original source cells in vivo but fail to provide customized nanoparticle surfaces with new or enhanced capabilities beyond natural cells. However, the field of drug lead discovery necessitates the acquisition of sufficient surface density of specific target membrane receptors, presenting a heightened demand for this technology. In this study, we developed a novel approach to fabricate high density of fibroblast growth factor receptor 4 (FGFR4) cell membrane-coated nanoparticles through covalent site-specific immobilization between genetically engineered FGFR4 with HaloTag anchor on cell membrane and chloroalkane-functionalized magnetic nanoparticles. This technique enables efficient screening of tyrosine kinase inhibitors from natural products. And the enhanced density of FGFR4 on the surface of nanoparticles were successfully confirmed by Western blot assay and confocal laser scanning microscopy. Further, the customized nanoparticles demonstrated exceptional sensitivity (limit of detection = 0.3 × 10–3 μg mL–1). Overall, the proposed design of a high density of membrane receptors, achieved through covalent site-specific immobilization with a HaloTag anchor, demonstrates a promising strategy for the development of cell membrane surface engineering. This approach highlights the potential of cell membrane coating technology for facilitating the advanced extraction of small molecules for drug discovery.

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Section: Resultscontrasting

confidence: 66%

Genetically Engineered Cell Membrane-Coated Nanoparticles with High-Density Customized Membrane Receptor for High-Performance Drug Lead Discovery

Bu,

Wu,

Zhao

et al. 2023

ACS Appl. Mater. Interfaces

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“…[11] Nevertheless, most functional materials used for the detection or removal of arsenic are employed separately. [14][15][16][17][18][19] Integrating both detection and removal functions into a single platform offers numerous advantages. [20][21][22][23][24][25][26] Therefore, there is a need for dualfunctional materials that combine these functions, but such materials are scarce in the literature.…”

Section: Introductionmentioning

confidence: 99%

Carbon Dots‐Embedded Silica Tubes: An Excitation‐Independent Yellow‐Emitting Turn‐On Probe for Simultaneous Detection and Removal of Inorganic Arsenic with In Vivo Tracking in Living Organisms

Yadav,

Choudhary,

Sonpal

et al. 2023

Small

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The environmental monitoring and remediation of highly toxic inorganic arsenic species in natural water are needed for the benefit of the ecosystem. Current studies on arsenic detection and removal often employ separate materials, which exhibit blue luminescence with fluorescence quenching, making them unsuitable for biological and environmental samples. In this study, carbon dot‐embedded mesoporous silica tubes functionalized with melamine are synthesized to address these limitations and enable specific and turn‐on probing of inorganic arsenic. The newly synthesized material demonstrates excitation‐independent yellow luminescence and can effectively detect both As (III) and As (V) at low detection limits (11 × 10−9 m, 11.2 × 10−9 m), well below the prescribed threshold limits in drinking water. It also exhibits a high adsorption capacity (≈125, 159 mg g−1) with fast kinetics. The material's applicability in environmental samples is validated through the successful quantification of arsenic in real samples with satisfactory recoveries. Moreover, the material shows recyclability for reuse, as demonstrated by its arsenic adsorption and desorption for several cycles under basic conditions. Additionally, the material's capability for monitoring arsenic in a biological sample (Artemia salina) is demonstrated through fluorescence imaging. The encouraging outcomes underscore the material's potential use in monitoring and mitigating arsenic in aqueous systems.

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Multivariate modeling and process optimization of Hg(II) remediation using solvothermal synthesized 2D MX/Fe3O4 by response surface methodology: characteristics and mechanism study

Indurkar

Raj

Kulshrestha

2023

Environ Sci Pollut Res

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Rationally designed in-chain porous metallo-polymeric microsphere: A highly efficient and regenerative scavenger for ultra-trace arsenic from water

Cited by 12 publications

References 71 publications

Genetically Engineered Cell Membrane-Coated Nanoparticles with High-Density Customized Membrane Receptor for High-Performance Drug Lead Discovery

Genetically Engineered Cell Membrane-Coated Nanoparticles with High-Density Customized Membrane Receptor for High-Performance Drug Lead Discovery

Carbon Dots‐Embedded Silica Tubes: An Excitation‐Independent Yellow‐Emitting Turn‐On Probe for Simultaneous Detection and Removal of Inorganic Arsenic with In Vivo Tracking in Living Organisms

Multivariate modeling and process optimization of Hg(II) remediation using solvothermal synthesized 2D MX/Fe3O4 by response surface methodology: characteristics and mechanism study

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