Rationale for the use of NSAIDs with antiseptic action for sore throat in the complex therapy of infectious and inflammatory diseases

Abstract

Sore throat is one of the most common symptoms with which patients seek an appointment with an otorhinolaryngologist, and also serve as the main subjective symptom of infectious and inflammatory diseases of the pharynx. Pain in the throat, making it difficult to swallow, colloquial speech can drastically reduce the quality of life of patients, almost completely turning them off from active personal, work and social life. At the same time, the increase in the intensity of pain in the throat serves as a diagnostic criterion for the growth of the local inflammatory process, leading to its complications (peritonsillitis, paratonsillar abscess, etc.). Given that the main etiopathogenetic factors of the infectious and inflammatory pathology of the throat are viral, bacterial infection and inflammation, antibacterial and anti-inflammatory therapy are the main points of application in the complex treatment of these diseases. The economic and practical inconveniences of the need to purchase a large number of drugs justify the relevance and practical significance of the use of drug release forms, including a combination of etiopathogenetically targeted substances. This article discusses the effectiveness and feasibility of using a combination of NSAIDs and an antiseptic in one preparation. The studied materials allow us to state that the use of both individual components of the drug and its combined composition in the treatment of infectious and inflammatory diseases of the throat is justified, which manifests itself in a fairly quick and complete relief of the symptoms of the disease without complications and side effects of the drug. A comparative evaluation of the effectiveness of mono and complex therapy indicates a significant advantage of complex treatment, which includes two active ingredients of NSAIDs and an antiseptic.