Rationale for the Inclusion of
Alpha-Adrenergic Blockade in
Benign Prostatic Hyperplasia
Treatment Guidelines

Roehrborn, Claus G.

doi:10.1159/000473819

Cited by 2 publications

(1 citation statement)

References 27 publications

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“…They have a low incidence of side effects [24], but such treatment is only cost effective in comparison to surgical procedures. It is still vital to assess the bothersomeness of the symptoms and to realise that any improvement, either in outflow obstruction or reduction in prostatic size, will only be marginal and unlikely to move men from an operative to a non-operative category or even to change men with moderate symptoms to those with minor symptoms.…”

Section: Drugs Used To Relieve Obstructionmentioning

confidence: 99%

Male Lower Urinary Tract Symptoms: Is Surgery Always Necessary?

Assassa¹,

Osborn²,

Castleden³

1998

Gerontology

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A transurethral resection of the prostate is a good operation to relieve bladder outflow obstruction and has a low incidence of complications. However, recent work suggests that many men with symptoms may not require an operation, and it can probably be delayed in a majority for many years. This may be particularly important in old and frail patients. Many men with outflow obstruction have irritative symptoms such as urgency, frequency and nocturia; these could be treated with anticholinergics, provided they have normal flow rates and small or absent residual urine volumes. Pharmacological treatment to relieve outflow obstruction is disappointing. There may be some benefit from α-adrenoreceptor antagonists, but the place for 5α-reductase inhibitors is still unsure. All drugs have side effects which are unacceptable in patients who are not bothered by their urinary symptoms and can wait for active treatment.

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Section: Drugs Used To Relieve Obstructionmentioning

confidence: 99%