Rational selection of an ideal oncolytic virus to address current limitations in clinical translation

Enhancing oncolytic virus efficiency with methionine and N-(3-aminoprolil)methacrylamide modified acrylamide cationic block polymer

“…An oncolytic virus is a high-efficiency tumor treatment method that can specifically infect and crack tumor cells 1–4 with many advantages, such as improving the immune microenvironment of the tumor and not being restricted by drug resistance. 5,6 So far, four oncolytic virus products, Delytact, Lmlygic, Oncorine, and Virgo, have been approved for intratumoral administration for tumor treatment.…”