“…The ribosome acts as a temperature sensor in Escherichia coli to coordinate metabolism and growth in response to the environment (VanBogelen and Neidhardt, 1990;Warner, 1999;Moss, 2004). Effective ribosomal biogenesis is tightly finetuned by cellular status (Lempiäinen and Shore, 2009) and variations in environmental conditions (Planta, 1997;Mayer and Grummt, 2006), such as ambient temperature (Kaczanowska and Rydén-Aulin, 2007;Al Refaii and Alix, 2009;Baliga et al, 2016). Aberrant sensitivity to temperature fluctuation is a hallmark of mutants with defects in ribosome biogenesis in E. coli (Guthrie et al, 1969;Dammel and Noller, 1993;Jones et al, 1996;Al Refaii and Alix, 2009;Mayerle and Woodson, 2013), yeast (Warner and Udem, 1972;Tollervey et al, 1993;Teyssier et al, 2003;Wan et al, 2015), and Arabidopsis (Ohbayashi et al, 2011;Huang et al, 2016;Liu et al, 2016).…”