Rational Design of Bio‐Inspired Peptide Electronic Materials toward Bionanotechnology: Strategies and Applications

Abstract

Biologically inspired peptide‐based materials, as novel charge transport materials, have gained increasing interest in bioelectronics due to their remarkable electrical properties and inherent biocompatibility. Extensive studies have shown that peptides can self‐assemble into a variety of hierarchical nanostructures with unique physical properties through supramolecular interactions. Therefore, peptide‐based materials hold great promise for applications in emerging electronic fields such as sensing, energy harvesting, energy storage, and electronic transmission. Herein, this work proposes a review article to summarize the rational design and research progress of peptide‐based materials and devices in bioelectronics. This work first introduces the design strategies and assembly mechanism for constructing high‐performance peptide‐based electronic materials and devices. In the following part, the applications of peptide‐based electronic materials and devices are systematically classified and discussed, including sensors, piezoelectric nanogenerators, electrodes, and semiconductors. Finally, the remaining challenges and future perspectives of peptide‐based bioelectronic materials and devices are presented. This work believes that this review will provide inspiration and guidance for the design and development of innovative peptide‐based smart materials in the field of bioelectronics.

Recent Advances in Biomimetics for the Development of Bio-Inspired Prosthetic Limbs

“…Dynamic bonds or polymers capable of undergoing reversible changes in response to external stimuli are commonly employed in this approach [98]. Furthermore, researchers are exploring the integration of sensors and actuators within self-repairing materials, enabling them to detect damage and initiate repair processes autonomously [99]. This realtime monitoring and repair capability closely mimic the sensory feedback and self-repair mechanisms observed in natural organisms [99,100].…”

“…Furthermore, researchers are exploring the integration of sensors and actuators within self-repairing materials, enabling them to detect damage and initiate repair processes autonomously [99]. This realtime monitoring and repair capability closely mimic the sensory feedback and self-repair mechanisms observed in natural organisms [99,100]. By integrating sensors, these materials can detect changes in their environment and respond accordingly, enhancing their ability to detect and repair damage in prosthetic limbs.…”