Rational design of amphiphilic BODIPY-based photosensitizers for multimodal imaging-guided phototherapy

Abstract

The design of effcient photosensitisers for cancer theranostics is of great importance, especially for multimodal-imaging-guided synergistic therapy. The key to achieving accurate imaging-guided phototherapy is to balance the energy distribution...

Nanoparticles Encapsulated in Red Blood Cell Membranes for Near-Infrared Second Window Imaging-Guided Photothermal-Enhanced Immunotherapy on Tumors

“…Integrated diagnosis and treatment strategies can improve the accuracy and precision of treatments and are highly beneficial in treating tumors − because drugs can be targeted and treatments can be monitored in real time. − In recent years, the integration of multiple components that have early tumor diagnosis and in situ treatment functions onto a nanoplatform has facilitated the development of multifunctional diagnostic and therapeutic agents that can monitor treatment efficacies and prognoses in real time . Presently, multimodal imaging, such as fluorescence and thermal imaging, and guided synergistic therapy, such as photothermal therapy (PTT), chemotherapy, and immunotherapy, are commonly integrated for diagnosis and treatment. − …”

Host–Guest Photosensitizer of a Cationic BODIPY Derivative and Cucurbit[7]uril for High-Efficiency Visible Light-Induced Photooxidation Reactions

“…Additionally, in its role as a photosystem, it has the ability to facilitate both type I and type II photooxidation reactions. The applications of this approach have been observed in various domains, including fluorescence imaging, probe labeling, ion recognition, pH recognition, photodynamic therapy (PDT), materials science, and other related disciplines. ,− Although there have been numerous studies on the various applications of BODIPY, there is an insufficient amount of research on its direct use as a PC for organic reactions. For example, Hu and co-workers fabricated supramolecular assembly through host–guest interactions between water-soluble pillar[5]­arene and an aggregation-induced emission (AIE) photosensitizer, which exhibit the ability to effectively generate 1 O 2 and can be used as PCs for the conversion of dopamine to polydopamine .…”