Ratiometric sensing of nerve agent mimic DCP through in situ benzisoxazole formation

Fluorescent probes for the detection of chemical warfare agents

“…100 In 2019, Ali et al reported a fluorescent probe, TPOD (72), which employed b-hydroxy oximes as a recognition unit for DCP detection. 101 This probe exhibited a low LOD of 0.14 mM by UV-vis absorption and 0.23 mM by fluorescence in CH 3 CN-H 2 O. TPOD was integrated into a test kit that can show dramatic changes in colour and fluorescence within 30 s in the presence of DCP. In 2019, Yang and co-workers designed and synthesized the fluorescent probe, PTS (73), for the detection of the nerve agent mimic DCP.…”

A benzothiazole-based dual reaction site fluorescent probe for the selective detection of hydrazine in water and live cells

“…Compounds 2-5 were synthesized according to the literature method. [49][50][51] Synthesis and characterization of the probe BTC Compound 5 (250 mg, 0.62 mmol), malonitrile (82.7 mg, 1.24 mmol) and NH 4 OAC (118.0 mg, 1.5 mmol) were dissolved in AcOH and refluxed in toluene (6 ml) for 12 hours. After refluxing for 12 hours, the mixture was poured into deionized water and extracted with ethyl acetate (30 ml × 3).…”

Triphenylamine-based small-molecule fluorescent probes

“…16a and b). 95 Probe 63 exhibits a ratiometric fluorescence change upon the addition of DCP. The authors proved that the stoichiometry of the formation of compound 63a between probe 63 and DCP is 1 : 1.…”