Rates and Trends of Pediatric Acute Lymphoblastic Leukemia — United States, 2001–2014

COVID‐19 and childhood acute lymphoblastic leukemia

“…Acute lymphoblastic leukemia (ALL), the most common form of childhood cancer, has an overall incidence in the United States of 34 cases/ million individuals <20 years of age with the peak incidence of 75.2 cases/ million occurring in children between the ages of 1‐4 years 1 . Hypotheses have been proposed, particularly by Dr Greaves, that account for the peak incidence in early childhood 2 .…”

Childhood acute leukemia in Guanajuato registered from a tertiary medical center

“…Whit respect, to the hereditary such as genetic susceptibility, disproportionate environmental exposure to household chemicals, or parents´ exposure to chemicals at work. 3 Studies of possible causes of pediatric leukemia have been associated with exposures to solvents, traffic, pesticides, tobacco smoke, radiation or specific nutritional exposures. 4 The child population with leukemia 5 when classified as severe corresponds to the myeloid leukemia.…”

“…We were suggest influence of petroleum hydrocarbons products with non-occupational sources of exposure exist, this support another reports about this problematic in different populations of children and adults. [1][2][3][4] In addition, we must recognize that urban centers and population growth in a large majority end up surrounding the industrial centers, which in turn has increased the exposure to waste, or air pollutions. In human beings and living animals, in this case also suspect infectious vectors by pets, 9 we have mechanisms that protect us from external factors, have repair systems for damages, defects, or removal of macromolecules that have suffered severe damage.…”

Exploring a potential mechanistic role of DNA methylation in the relationship between in utero and post‐natal environmental exposures and risk of childhood acute lymphoblastic leukaemia

“…Acute lymphoblastic leukaemia (ALL) is the most common form of childhood cancer [1]. Although survival rates have improved, with 5-year survival rate increasing from 60-90% [2], overall incidence of childhood ALL has been slowly increasing [3].…”

“…Acute lymphoblastic leukaemia (ALL) is the most common form of childhood cancer. 1 Although survival rates have improved, with 5-year survival rate increasing from 60 to 90%, 2 overall incidence of childhood ALL has been slowly increasing. 3 Genetic aberrations such as chromosomal translocations and hyperdiploidy have been suggested to play a role in ALL disease development, yet these events alone are not sufficient for disease manifestation.…”