Rate of Rise of Alveolar Xenon Concentration in Man

Abstract

The rate of rise of alveolar xenon concentration toward a fixed inspired level was measured in four adult male volunteers. At 1 minute the ratio of end-tidal to inspired xenon concentration was 0.76, at 2 minutes it was 0.38, at 5 minutes it was 0.96, and at 20 minutes it was 0.97. These results agree with those predicted from xenon solubility in blood and tissues, and were closely simulated with a passive resistancecapacitor analogue.