Rate of progression of subclinical hypothyroidism to overt hypothyroidism: a 10-year retrospective study from UAE

Alameri, Majid; Wafa, Wafic; Moriarty, Maura; Lessan, Nader; Barakat, Maha T

doi:10.1530/endoabs.59.p202

Cited by 4 publications

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“…In this study, more overweight and obese people were observed in the control group due to their lifestyle and food habits and fewer physical activities. Various researchers from Arab countries corroborated the finding of obesity in the study group of females [3,29]. Likewise, researchers from other countries observed similar findings [30,31].…”

Section: Age and Bmisupporting

confidence: 69%

“…Among females in the USA and Europe, the prevalence rate of hypothyroidism ranges from 1% to 2%, mainly in older females [2]. However, for United Arab Emirates females, the hypothyroidism prevalence rate has been 6.5% for the last ten years [3]. Furthermore, the hypothyroidism prevalence rate among 20-to 40-year-old females in Libya is 6.18%, and in Saudi Arabia, it is 47.34% [4,5].…”

Section: Introductionmentioning

confidence: 99%

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Probability of Concurrent Deficiency of Vitamin D and Iron in Hypothyroidism: A Cross-Sectional Study

Shimmi¹,

Eldosouky²,

Parash³

et al. 2023

Cureus

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Background: Hypothyroidism is the most common pathophysiological condition that affects mostly females in both developed and developing countries. Data on hypothyroidism among adult females are essential to understand the underactive status of the thyroid gland among the female population and its correlated effects on a deficiency of vitamin D and iron, as effective prevention of osteoporotic changes and iron deficiency anemia is possible. Therefore, the present study was designed to investigate the probability of concurrent iron and vitamin D deficiency among the adult hypothyroid female population of Abu Dhabi, UAE.Materials and methods: This cross-sectional study was carried out from September 2019 to July 2021 among 500 adult females aged 18 to 45 years old in Sheikh Shakhbout Medical City (SSMC) and Sheikh Khalifa Medical City (SKMC), Abu Dhabi, UAE. After obtaining written informed consent, subjects' demographic characteristics (sun exposure, dressing code, food consumption), anthropometry (height, weight, BMI), and biochemical parameters (thyroid profile, vitamin D profile, iron profile, and blood indices) were measured.Results: In this study, serum vitamin D and iron levels were significantly (p<0.01) decreased in the hypothyroid female group (study group). The serum vitamin D and iron levels showed a significant negative (p<0.01) correlation with thyroid-stimulating hormone (TSH). Out of 250 study group participants, 61 had a concurrent deficiency of serum vitamin D and iron, yielding a probability (P of low vitamin D and iron and hypothyroidism) of 0.244, which indicates that if 1000 hypothyroid patients are tested for serum vitamin D and iron levels, 24 patients are probable to have low vitamin D and iron. Conclusion:The study concluded that vitamin D and iron bi-deficiency were observed in adult hypothyroid females in Abu Dhabi, UAE. So, the routine check-up of thyroid function and vitamin D and iron profiles should be done early. Therefore, early vitamin D and iron deficiencies can be detected, and supplements can be given to prevent further health complications like osteoporosis and iron deficiency anemia.

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Section: Age and Bmisupporting

confidence: 69%

Section: Introductionmentioning

confidence: 99%

Probability of Concurrent Deficiency of Vitamin D and Iron in Hypothyroidism: A Cross-Sectional Study

Shimmi¹,

Eldosouky²,

Parash³

et al. 2023

Cureus

View full text Add to dashboard Cite

show abstract

“…Vitamin D3 had an upper normal limit in hypothyroidism compared to sufficiency in hyperthyroidism. (Alameri, Wafa, Moriarty, Lessan, & Barakat, 2018). The mean level of vitamin B12 in hypothyroidism patients was 159.23 ng/ml compared to 209.69 ng/ml in hyperthyroidism patients, indicating that hypothyroidism has a greater influence on vitamin B12 than hyperthyroidism.…”

Section: Discussionmentioning

confidence: 85%

impact of vitamin D3 and B12 in patients with thyroid disorders in Kirkuk –Iraq

Kadhim,

Hussain

2022

ijhs

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Background: Thyroid disorders are common among Iraqis, and hypothyroidism has grown after the 2003 and 2014 events. Anemia and osteoporosis are caused by a lack of ferritin, iron, vitamins B12 and folic acid, as well as vitamin D3. Objectives: to determine thyroid status in people in Kirkuk province and to detect its relation to vitamin D3, B12 as well as its impact on main blood components. Setting: A preliminary cross-sectional study was conducted involving 105 patients attending Ibn-Nafees private medical lab. from both gender, suffering from thyroid dysfunction. their average ages were 38.12± 1.4 years. Methods: Thyroid hormones (T3), thyroid hormones (T4), and thyroid-stimulating hormone (TSH) were measured using the Mini-Vidas machine, and vitamin B12 was evaluated using an ELISA. The Sysmex XN-350 auto-analyzer was used to determine the complete blood count (CBC). Results: The total abnormality rate for thyroid function was 14.28 percent. This rate accounts for 9.52 percent of cases of hyperthyroidism and 4.76 percent of cases of hypothyroidism. Thyroid dysfunction is more prevalent in urban areas than in rural areas. Vitamin B12 insufficiency was often seen in hypothyroid individuals. There was a substantial correlation between hypothyroidism and patient gender.

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“…Even in UAE, a researchers revealed that females are more likely to develop overt hypothyroidism [17].…”

Section: Discussionmentioning

confidence: 99%

Prevalence Of Thyroid Hormones Test Abnormality In Females At Reproductive Age Attending Al-batool Maternity Teaching Hospital

Salman¹

2023

DJM

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Background: Although there is little information about the prevalence of thyroid disorders in young women, but they are common in Iraq. Objective: To prevalence of thyroid hormones test abnormality in females at reproductive age attending al-batool maternity teaching hospital Patients and Methods: This study involved 1570 of reproductive female ages patients at the Al-batool Maternity Hospital in Diyala Province, Iraq. Serum levels of T3, T4, and TSH were measured in this study. According to the conventional definitions of T3, T4, and TSH levels of overt hyper- and hypothyroidism patients were grouped according to their thyroid status at the time of testing. Results: A total of 1570 subjects were screened of whom 152 subjects (18.6%) had abnormal TSH. The overall prevalence of hyperthyroidism with elevated TSH was 17.4%, of which 1.2% had hypothyroidism with elevated TSH. A low TSH was seen in 1.3% of the study population (P= 0.001). Generally, thyroxin hormone (T4) abnormalities were totaled at 12.02%, of which 10.22% were hypothyroidism and 1.8% was hyperthyroidism. Furthermore, the triiodothyroxin hormone T4 abnormality percentage was 14.84%, compared to hypothyroidism of 3.12% and hyperthyroidism of 11.72%. Conclusion: Thyroid dysfunction was common in young women. Therefore, females more susceptible to thyroid disorders. Keywords: prevalence, thyroid‑stimulating hormone, hyperthyroidism, hypothyroidism, Iraq, women

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Rate of progression of subclinical hypothyroidism to overt hypothyroidism: a 10-year retrospective study from UAE

Cited by 4 publications

References 0 publications

Probability of Concurrent Deficiency of Vitamin D and Iron in Hypothyroidism: A Cross-Sectional Study

Probability of Concurrent Deficiency of Vitamin D and Iron in Hypothyroidism: A Cross-Sectional Study

impact of vitamin D3 and B12 in patients with thyroid disorders in Kirkuk –Iraq

Prevalence Of Thyroid Hormones Test Abnormality In Females At Reproductive Age Attending Al-batool Maternity Teaching Hospital

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