Rate of plaque formation – some clinical and biochemical characteristics of “heavy” and “light” plaque formers

Abstract

Simonsson T, Ronstrom A, Rundegren J, Birkhed D: Rate of plaque formation -some clinical and biochemical characteristics of "heavy" and "light" plaque formers, Scand J Dent Res 1987; 95: 97-103, Abstract -The purpose of the present study was to give a clinical and biochemical characterization of two groups of individuals witb different rates of plaque formation. From 133 individuals, 9 "heavy" and 10 "light" plaque formers were selected. The mean plaque index after 3 days of plaque accumnlation, on buccal surfaces of premolars and first molars, was 2,6 for the "heavy" and 0,6 for tbe "iighl" plaque formers. The foUowing variables were determined: periodontal status, DFS, dietary habits, salivary secredcn rate and buffer effect, S, mutans and lactobacillus counts in saliva, salivar)' content of IgA, lactoferrin, lactoperoxidase and lysozyme, sahva-induced aggregation of certain oral streptococci, gel electrophoresis of saliva, amino acid composition of saliva and tbe acquired pellicle and retention depth of the dentogingival area. Comparing the two groups of plaque formers, statistically significant diiferences were found for the following three variables: parotid saliva-induced aggregation of a strain of S, sanguis, content of glutamic acid in the acquired pellicle and retention depth of the dentogingival area for maxillary premolars. Large variations for all studied variables were found, both within and between the groups. Several factors may be involved in plaque formation and none of the studied variables alone could explain the large difference in the amount of plaque formed after 3 days between the "heavy" and "light" plaque formers.

Agglutinin and Acidic Proline-rich Protein Receptor Patterns May Modulate Bacterial Adherence and Colonization on Tooth Surfaces

“…A polymorphism of S. mutans binding agglutinins has been demonstrated (Kishimoto et al, 1990). Some studies, though not others (Lenander-Lumikari et al, 1992;Tenovuo et al, 1992), have associated the level of aggregation or agglutinins with the plaque formation rate (Magnusson et al, 1976;Simonsson et al, 1987), the number of indigenous S. mutans (Emilson et al, 1989;Carlen et al, 1996), and dental caries (Rosan et al, 1982). Both agglutinins and APRPs may thus be important determinants of individual colonization patterns and host susceptibility to dental diseases.…”

Does Variability in Salivary Protein Concentrations Influence Oral Microbial Ecology and Oral Health?

“…Salivary variables have been compared between small groups of "heavy" and "light" plaque-formers identified by the screening of a large population. No differences were seen with the exception of bacterial aggregating capacity, which was higher in light-plaque-formers (Simonsson et al, 1987). Total PRP likewise have shown an inverse relationship with plaque accumulation scores (Kousvelari et al, 1980).…”

The Plaque Inhibitory Effect of Aloe Vera Mouthrinse in A Four Day De Novo Plaque Formation Model- A Randomized, Double Blind Crossover Study

“…[17][18][19][20][21][22] A particular advantage of a crossover design is that each subject serves his or her own control so it reduces the influence of confounding that arises because of individual variables that effect plaque formation like the salivary flow and composition, existing plaque retention sites, pre-existing gingivitis, dietary habits, and the composition of pellicle. [23,24] Also optimal crossover designs are statistically significant so require fewer subjects than non crossover design. To decrease the "carryover effect" between treatments encountered in crossover trials, a 10 day wash out period was followed in our study.…”