Rate-dependent fracture behavior of tough polyelectrolyte complex hydrogels from biopolymers

Xiao, Zhenhua; Liu, Yong; Yang, Junsheng; Jiang, Han; Tang, Liqun; Chen, Heng; Sun, Tao Lin

doi:10.1016/j.mechmat.2021.103785

Cited by 9 publications

(5 citation statements)

References 35 publications

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“…Taken together, certain impact resistance and good elastic recovery ability would endow the hydrogels with good fatigue durability for long-term performance and the stability of the artificial vascular material. It also demonstrates that the dynamic double network and the reversibility of dynamic imine bonds are beneficial to maintaining the mechanical stability and fatigue durability of hydrogels during compression …”

Section: Resultsmentioning

confidence: 99%

“…It also demonstrates that the dynamic double network and the reversibility of dynamic imine bonds are beneficial to maintaining the mechanical stability and fatigue durability of hydrogels during compression. 42 Both tensile and compression tests demonstrated that PCO hydrogels with proper CMCS/OCD contents, like PCO-2, exhibited ideal mechanical properties. When subjected to dynamic loads, the dual-network structure of the hydrogel can disperse stress and absorb energy, thereby enhancing the toughness and fatigue resistance of the material.…”

Section: Mechanical Properties Of Hydrogelsmentioning

confidence: 96%

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Dynamically Cross-Linked Double-Network Hydrogels with Matched Mechanical Properties and Ideal Biocompatibility for Artificial Blood Vessels

Jia,

Huang,

Meng

et al. 2024

ACS Appl. Mater. Interfaces

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Vessel transplantation is currently considered the "gold standard" treatment for cardiovascular disease. However, ideal artificial vascular grafts should possess good biocompatibility and mechanical strength that match those of native autologous vascular tissue to promote in vivo tissue regeneration. In this study, a series of dynamic cross-linking double-network hydrogels and the resultant hydrogel tubes were prepared. The hydrogels (named PCO), composed of rigid poly(vinyl alcohol) (PVA), flexible carboxymethyl chitosan (CMCS), and a cross-linker of aldehydebased β-cyclodextrin (OCD), were formed in a double-network structure with multiple dynamical cross-linking including dynamic imine bonds, hydrogen bonds, and microcrystalline regions. The PCO hydrogels exhibited superior mechanical strength, good network stability, and fatigue resistance. Additionally, it demonstrated excellent cell and blood compatibility. The results showed that the introduction of CMCS/OCD led to a significant increase in the proliferation rate of endothelial cells seeded on the surface of the hydrogel. The hemolysis rate in the test was lower than 0.3%, and both protein adsorption and platelet adhesion were reduced, indicating an excellent anticoagulant function. The plasma recalcification time test results showed that endogenous coagulation was alleviated to some extent. When formed into blood vessels and incubated with blood, no thrombus formation was observed, and there was minimal red blood cell aggregation. Therefore, this novel hydrogel tube, with excellent mechanical properties, exhibits antiadhesive characteristics toward blood cells and proteins, as well as antithrombotic properties, making it hold tremendous potential for applications in the biomedical and engineering fields.

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Section: Resultsmentioning

confidence: 99%

Section: Mechanical Properties Of Hydrogelsmentioning

confidence: 96%

Dynamically Cross-Linked Double-Network Hydrogels with Matched Mechanical Properties and Ideal Biocompatibility for Artificial Blood Vessels

Jia,

Huang,

Meng

et al. 2024

ACS Appl. Mater. Interfaces

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“…However, gels relying solely on physical crosslinking exhibit poor mechanical properties, limiting their application range. Chemically crosslinked gels, on the other hand, possess stronger stability and mechanical properties, thus finding wider applications [11]. Nevertheless, commonly used crosslinking agents, such as glutaraldehyde and epichlorohydrin, are toxic and incompatible with environmentally friendly cellulose-based materials [7,12].…”

Section: Introductionmentioning

confidence: 99%

Silicon-Doped Carbon Dots Crosslinked Carboxymethyl Cellulose Gel: Detection and Adsorption of Fe3+

Zhao,

Jing,

Shen

et al. 2024

Gels

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The excessive emission of iron will pollute the environment and harm human health, so the fluorescence detection and adsorption of Fe3+ are of great significance. In the field of water treatment, cellulose-based gels have attracted wide attention due to their excellent properties and environmental friendliness. If carbon dots are used as a crosslinking agent to form a gel with cellulose, it can not only improve mechanical properties but also show good biocompatibility, reactivity, and fluorescence properties. In this study, silicon-doped carbon dots/carboxymethyl cellulose gel (DCG) was successfully prepared by chemically crosslinking biomass-derived silicon-doped carbon dots with carboxymethyl cellulose. The abundant crosslinking points endow the gel with excellent mechanical properties, with a compressive strength reaching 294 kPa. In the experiment on adsorbing Fe3+, the theoretical adsorption capacity reached 125.30 mg/g. The introduction of silicon-doped carbon dots confers the gel with excellent fluorescence properties and a good selective response to Fe3+. It exhibits a good linear relationship within the concentration range of 0–100 mg/L, with a detection limit of 0.6595 mg/L. DCG appears to be a good application prospect in the adsorption and detection of Fe3+.

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“…[27][28][29][30][31] Viscoelasticity is an intrinsic property of polymeric materials and soft biotissues. [32][33][34][35][36][37] Tough hydrogels are usually nonresponsive to external stimuli, and have dense and robust associative interactions as physical cross-links that dissipate energy under loading. [6][7][8][9][10][11] Such a toughening mechanism imparts the gels with intrinsic and notable viscoelasticity.…”

Section: Introductionmentioning

confidence: 99%

“…The viscoelasticity of tough gels including the recovery speed after unloading can be tailored by tailoring the supramolecular networks and environmental conditions. [35][36][37] Such substantial viscoelasticity affords tough gels with poor resilience that is unfavorable for some applications, yet it provides a possible mechanism for timedependent release of elastic energy stored at pre-stretching. [38][39][40] We envision to harness the viscoelastic recovery and thus realize programmed morphing by engineering the viscoelasticity mismatch in tough gels.…”

Section: Introductionmentioning

confidence: 99%

Engineering viscoelastic mismatch for temporal morphing of tough supramolecular hydrogels

et al. 2023

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Rate-dependent fracture behavior of tough polyelectrolyte complex hydrogels from biopolymers

Cited by 9 publications

References 35 publications

Dynamically Cross-Linked Double-Network Hydrogels with Matched Mechanical Properties and Ideal Biocompatibility for Artificial Blood Vessels

Dynamically Cross-Linked Double-Network Hydrogels with Matched Mechanical Properties and Ideal Biocompatibility for Artificial Blood Vessels

Silicon-Doped Carbon Dots Crosslinked Carboxymethyl Cellulose Gel: Detection and Adsorption of Fe3+

Engineering viscoelastic mismatch for temporal morphing of tough supramolecular hydrogels

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