Rat Bite Fever Caused by Spirillum Minus Treated With Penicillin

Frank, Lawrence

doi:10.1001/archderm.1948.01520140123015

Cited by 7 publications

(2 citation statements)

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“…However, infections are increasing, especially in children, because of the popularity of rodents as pets . Transmission also occurs by ingesting food contaminated by urine of colonized rats, causing a syndrome known as “Haverhill fever.”…”

Section: Discussionmentioning

confidence: 99%

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Fever, Rash, and Migratory Polyarthralgias

Gaston

Peaper

Advani

2019

JAMA

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A 24-year-old woman who worked on a farm in Connecticut developed fever, chills, vomiting, and a truncal maculopapular rash 3 weeks before presentation. One week after symptom onset, she remained febrile (maximum temperature, 39.6°C [103.2°F]) and the rash spread to her palms and soles, with some progression to pustules (Figure, left panel). She developed right knee pain, followed by pain in other joints. Two weeks after symptom onset, she presented to a local emergency department, reporting inability to stand due to severe joint pain. Results of tests for sexually transmitted infections and respiratory viruses were negative. She was presumptively diagnosed with a viral illness and discharged home with supportive care. Approximately 3 weeks after symptom onset, she presented to the emergency department again with persistent fever, worsening arthralgia, back pain, and progressive purpuric and pustular rash. Her vital signs were unremarkable. White blood cell count was 12 100/μL (reference range, 4000/μL-10 000/μL), with 84% neutrophils. Urinalysis results and levels of serum electrolytes and liver enzymes were within normal limits. Gram stain of blood culture is shown in the Figure (right panel).

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Section: Discussionmentioning

confidence: 99%

“…4 Transmission also occurs by ingesting food contaminated by urine of colonized rats, causing a syndrome known as "Haverhill fever." 5 Rat bite fever is characterized by fever, chills, headache, and vomiting 3 to 10 days after exposure. Without treatment, fever typically follows a relapsing-remitting pattern.…”

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confidence: 99%