Rat amygdaloid neuron responses during auditory discrimination

Muramoto, Ken-ichiro; Ono, Taketoshi; Nishijo, Hisao; Fukuda, Masaji

doi:10.1016/0306-4522(93)90411-8

Cited by 118 publications

(104 citation statements)

References 61 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This is comparable to the percentage of correlated BLA neurons recorded in prior conditioning studies (Muramoto et al, 1993;Quirk et al, 1995). Twenty-eight neurons showed correlates that centered on reward acquisition at the 1 2 3 4…”

Section: Cell Classificationsupporting

confidence: 79%

“…Analysis of neural firing when rats revisited arms that they had already retrieved chocolate milk from showed an absence of the postencounter effect in most Such data suggest that the sensory or motor consequences of drinking may play an important role in the coding of postencounter neurons during this navigational task. Activity of amygdala neurons to food or liquid reward has been documented previously in the monkey (Nishijo et al, 1988b;Sanghera et al, 1979) and the rat (Muramoto et al, 1993) during sensory discrimination, and it is known that the amygdala receives extensive inputs from olfactory and gustatory sensory areas (for reviews, see Amaral, Price, Pitkanen, & Carmichael, 1992;De Olmos, Alheid, & Beltramino, 1985; see also Luskin & Price, 1983;Ottersen, 1982;Turner & Herkenham, 1991).…”

Section: Discussionmentioning

confidence: 93%

“…This provides an extension from previous research using classical conditioning techniques. Muramoto et al (1993) found that BLA neurons were more likely than centromedial amygdala cells to differentiate between cues that distinguished between two rewards of the same positive valence. The current experiment further demonstrates BLA complexity by showing that the BLA is able to incorporate more than one cue or cue array into the same reward representation.…”

Section: Discussionmentioning

confidence: 97%

See 2 more Smart Citations

Characteristics of basolateral amygdala neuronal firing on a spatial memory task involving differential reward.

Pratt¹,

Mizumori²

1998

Behavioral Neuroscience

View full text Add to dashboard Cite

Previous research has shown that spatial, movement, and reward information is integrated within the ventral striatum (VS). The present study examined the possible contribution of the basolateral nuclei of the amygdala (BLA) to this interaction by examining behavioral correlates of BLA neurons while rats performed multiple memory trials on an 8-arm radial maze. Alternate arms consistently held 1 of 2 different amounts of reward. Recorded cells were correlated with motion, auditory input, space, and reward acquisition. Reward-related units were found that anticipated reward encounter, that responded during reward consumption, and that differentiated between high and low reward magnitude. This is consistent with the hypothesis that BLA neurons may provide the VS with reward-related information that could then be integrated with spatial information to ultimately affect goal-directed behavior. Past research into the role of the amygdala in animal behavior has demonstrated that it is an important substrate for the association of cues with their affective significance.

show abstract

Section: Cell Classificationsupporting

confidence: 79%

Section: Discussionmentioning

confidence: 93%

Section: Discussionmentioning

confidence: 97%

See 1 more Smart Citation

Characteristics of basolateral amygdala neuronal firing on a spatial memory task involving differential reward.

Pratt¹,

Mizumori²

1998

Behavioral Neuroscience

View full text Add to dashboard Cite

show abstract

“…4 and 5 compare simulated cell activations and electrophysiological discharge profiles for cell types, including ITA (anterior inferotemporal cortex), lateral orbitofrontal cortex (ORB), medial orbitofrontal cortex (MORB), basolateral amygdala (AMYG), lateral hypothalamic output (LH_out) cells, and lateral hypothalamic gustatoryreceptive cells (LH_gus). Cells in the AMYG discriminate between rewarding and aversive stimuli and are modulated by hunger and satiety (Muramoto et al, 1993;Yan and Scott, 1996). Nishijo, et al (1988a, b) reported that some AMYG cells are multimodal, motivationallymodulated, and respond in a food-specific fashion.…”

Section: Model Inputs and Outputs The Neural Model Inmentioning

confidence: 99%

“…Specific cells prefer either appetitive or aversive stimuli and do not respond strongly to both. Muramoto et al (1993)]. 5b: Electrophysiological response profile recorded from an LH 'opposite cell' during the performance of the CS Task is shown adjacent to the simulated activity of LH output cells during the same task [Reprinted with permission from Ono et al (1986a) and Nakamura and Ono (1986)].…”

Section: Model Inputs and Outputs The Neural Model Inmentioning

confidence: 99%

Dopaminergic and non-dopaminergic value systems in conditioning and outcome-specific revaluation

2008

View full text Add to dashboard Cite

Light and electron microscopic study of cholinergic and noradrenergic elements in the basolateral nucleus of the rat amygdala: Evidence for interactions between the two systems

Nishijo

Wang

et al. 2001

J of Comparative Neurology

View full text Add to dashboard Cite

Pharmacological studies have suggested that the cholinergic (ACh) and noradrenergic (NA) systems in the amygdala (AM) play an important role in learning and memory storage and that the two systems interact to modulate memory storage. To obtain anatomical evidence for the interaction, the organization of the ACh and NA fibers in rat AM was investigated by immunocytochemistry for choline acetyltransferase (ChAT) and dopamine-beta-hydroxylase (DBH) in conjunction with light, confocal laser scanning, and electron microscopy (LM, CLSM, and TEM, respectively). LM showed that the ChAT immunoreactivity was densest in the basolateral nucleus (BL), whereas the DBH immunoreactivity was densest in the posterior BL. CLSM demonstrated that the ChAT-immunoreactive profiles in the BL were frequently located in juxtaposition to the DBH-immunoreactive axons. The TEM observations were as follows: The majority of the synapses formed by ChAT-immunoreactive terminals were symmetric, but DBH-immunoreactive axons formed both asymmetric and symmetric synapses. The ChAT-immunoreactive terminals usually established the symmetric synaptic contacts with the DBH-immunoreactive terminals and varicosities. The DBH-immunoreactive terminals formed the asymmetric synapses with the ChAT-immunoreactive dendrites of the intrinsic neurons within the AM. The results provide anatomical substrates for mnemonic functions of the ACh and NA systems and for the interactions between the two systems in the AM.

show abstract

Rat amygdaloid neuron responses during auditory discrimination

Cited by 118 publications

References 61 publications

Characteristics of basolateral amygdala neuronal firing on a spatial memory task involving differential reward.

Characteristics of basolateral amygdala neuronal firing on a spatial memory task involving differential reward.

Dopaminergic and non-dopaminergic value systems in conditioning and outcome-specific revaluation

Light and electron microscopic study of cholinergic and noradrenergic elements in the basolateral nucleus of the rat amygdala: Evidence for interactions between the two systems

Contact Info

Product

Resources

About