Rasio Low Density Lipoprotein dan High Density Lipoprotein pada Preeklamsi Berat dibandingkan dengan Kehamilan Normal di Rumah Sakit Dr. Hasan Sadikin Bandung

Abstract

This study aims to distinguish level of (LDL/HDL) and Low Density Lipoprotein/High Density Lipoprotein ratio in severe preeclampsia patient compared to normal pregnancy. Method: The study design was comparative cross-sectional study with consecutive sampling method that compared the laboratory results of LDL, HDL and ratio LDL/HDL that met the inclusion criteria. Subjects of this study were severe preeclampsia and normal pregnancy patient that fulfilled the inclusion criteria (n=60) in Dr. Hasan Sadikin General Hospital Bandung during August-September 2017. Result: It is revealed that the differences in level of LDL and LDL/HDL ratios in both groups were significant with p value ≤ 0,05. But there were no differences in HDL level. Increased level of LDL/HDL ratio in pregnancy was related to increased risk of preeclampsia with cutoff point> 2,632. If the increased level of LDL/HDL above cutoff point then the insident of severe preeclampsia increased 21,36 times. Conclusion: It was concluded that level of LDL and LDL/HDL ratios in severe preeclampsia were higher than in normal pregnancy. The increased LDL/HDL ratio of > 2.632 increased the risk of severe preeclampsia by 21.36 times.