Rash associated with pandemic (H1N1) influenza

Abstract

Figure 1: Maculopapular rash on the abdomen of a 44-year-old man with pandemic (H1N1) influenza.

During Influenza Season: All Influenza-Like Illnesses Are Not Due to Influenza: Dengue Mimicking Influenza

“…Rash is uncommon with adult influenza and when it occurs in children it is usually maculopapular and truncal and does not usually involve the extremities. It was thought that because of the pruritic nature of the rash, that it could be due to the neuraminidase inhibitor that she was taking (4)(5)(6). Although cutaneous and neurologic adverse side effects of oseltamivir are most common in children, it was not unreasonable to consider that the rash was a possible cutaneous manifestation of oseltamivir.…”

Skin rash and subconjunctival haemorrhage in an adult with pandemic H1N1 influenza

“…The typical characteristics are also varied with some individuals having a discrete appearance while still in others the rash can become confluent as in this patient. The diversifying nature of the rash is also highlighted by its distribution which can be widespread5 or localised to certain parts of the body, like the abdomen 6. The histopathological features underlying the rash in influenza include focal vacuolar alteration of the dermo-epidermal junction, necrotic keratinocytes and a superficial lymphocytic infiltration 12 13.…”

Viral exanthems

“…Although rash is uncommon in influenza, cutaneous manifestations have been reported with influenza A (H1N1)pdm09, A/H7N9 and influenza B [50][51][52][53]. A confluent maculopapular rash that spares the face and palmoplantar surfaces has been observed in influenza A (H1N1)pdm09 infection [51].…”