Rare solitary metastasis to subcutaneous tissue from choriocarcinoma of testis

Winter, Chester C.; Trepashko, Donald W.

doi:10.1016/0090-4295(89)90276-8

Cited by 15 publications

(15 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the last two cases, the patients were treated with orchiectomy, intense chemotherapy and, in the last case, radiotherapy. Both patients responded to the treatment, as evi-denced by decreased ttimor progression and a striking decrease of serum hGG (10,11).…”

Section: Discussionmentioning

confidence: 87%

Choriocarcinoma presenting as a cutaneous metastasis

et al. 1995

View full text Add to dashboard Cite

The rare presentation of choriocarcinoma as a cutaneous metastasis in a 23-year-old male is reported. Histological and immunohistochemical analysis of the biopsy material demonstrated two distinct cell populations, syncytiotrophoblasts and cytotrophoblasts, with syncytiotrophoblasts strongly positive for human chorionic gonadotropin antigen. Subsequent clinical evaluation revealed a testicular tumor with metastases to lungs, brain, liver and kidney and increased serum levels of human chorionic gonadotropin. The patient died shortly after diagnosis due to complications of metastatic disease despite chemotherapy.

show abstract

Section: Discussionmentioning

confidence: 87%

Choriocarcinoma presenting as a cutaneous metastasis

et al. 1995

View full text Add to dashboard Cite

show abstract

“…Discolo and Dispaquale reported a case of testicular seminoma with cervical lymphadenopathy as the presenting symptom [7]. Costal bones, brain, spleen, paracolic gutter, urethra, inferior vena cava, pancreatic and subcutaneous tissue have been reported as rare metastatic locations of primary testicular cancer but not as the presenting manifestation [8-14] (table 1). In our patient the painless cervical enlargement was due to the growing mediastinal choriocarcinoma and is, to our knowledge, the first case of concurrent testicular seminoma and mediastinal choriocarcinoma ever reported.…”

Section: Discussionmentioning

confidence: 99%

Concurrent development of testicular seminoma and choriocarcinoma of the superior mediastinum, presented as cervical mass: a case report and implications about pathogenesis of germ-cell tumours

et al. 2006

View full text Add to dashboard Cite

Background: Synchronous presentation of more than one germ cell tumours of different histology in the same patient is considered to be very rare. In these cases of multiple germ cell tumours, strong theoretical and clinical data suggest an underlying common pathogenetic mechanism concerning genetic instability or abnormalities during the pluripotent embryonic differentiation and maturation of the germ cell.

show abstract

“…Overall, 15 cases of skin metastases have been reported since 1974 [2]. Only seven of those patients had metastatic choriocarcinoma of testicular origin [1,[5][6][7][8].…”

Section: Discussionmentioning

confidence: 99%