Rare pattern of relapse to the pancreas and bilateral extraocular muscles in paediatric alveolar rhabdomyosarcoma

Ryan, Anne L; Nagarajan, Lakshmi; Alessandri, Angela J.; Gottardo, Nicholas G.; Kotecha, Rishi S.

doi:10.1111/jpc.13497

Cited by 2 publications

(2 citation statements)

References 7 publications

(8 reference statements)

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“…Studies have shown that the metatases of alveolar subtype tends to involves the bones. On the other hand, metastases in the bone marrow, pancres or in the orbit are extremely rare and shows worse prognosis (3)(4)(5)(6).…”

Section: Introductionmentioning

confidence: 99%

Alveolar rhabdomyosarcoma mimicking acute leukemia in an adolescent with deep venous thrombosis – case presentation

Vodă¹,

Leonte²,

Otelea³

et al. 2019

Ro J Pediatr.

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Rhabdomyosarcoma is the most common type of soft-tissue sarcoma, who invade and destroy nearby tissues. Rhabdomyosarcoma has defective myogenic differentiation and the alveolar subtype is the most aggressive, with hithgrade malignancy. We present the case of a 13-years-old girl, with a history of pain, functional impairment, red skin colour and swollen of the left thigh. The investigations have shown thrombosis on the left femoral and iliac vein, thrombosis that resulted from genetic predisposition together with the mechanisme of paraneoplastic thrombosis. The imagistic investigation documented retroperitoneal adenopathic masses encompassing the large vesels, gluteal and perianal mases, solid mass in the pancreatic head and multiple bone nodular lesions. The nonhematopoietic malignancies has masquerading acute leukemia on the bone marrow aspirate with atypical blasts (80% from cells population). The histological examination of the biopsy sample following excision of the left inguinal lymphadenopaty have revealed the final diagnosis: Stage IV alveolar rhabdomyosarcoma, with bone marrow infiltration and multiple metastases (inguinal, pelvic, periaortic, perihepatic), pancreatic and orbital metastases.

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Section: Introductionmentioning

confidence: 99%

Alveolar rhabdomyosarcoma mimicking acute leukemia in an adolescent with deep venous thrombosis – case presentation

Vodă¹,

Leonte²,

Otelea³

et al. 2019

Ro J Pediatr.

View full text Add to dashboard Cite

show abstract

“…Subtipul alveolar prezintă metastaze la nivel osos mai frecvent faţă de celelalte tipuri. Pe de altă parte, infiltrările neopla-zice medulare, pancreatice şi orbitale sunt rare, iar atunci când există, sugerează un prognostic prost (3)(4)(5)(6). Diagnosticul de certitudine este histologic, iar examinarea RMN ajută la decelarea localizării, limitării şi relaţiei tumorii primare cu structurile din vecinătate.…”

Section: Introducereunclassified

Rabdomiosarcomul alveolar mimând leucemia acută la o adolescentă cu tromboză venoasă profundă – caz clinic

Vodă¹,

Leonte²,

Oţelea³

et al. 2019

Ro J Pediatr.

View full text Add to dashboard Cite

show abstract

Rare pattern of relapse to the pancreas and bilateral extraocular muscles in paediatric alveolar rhabdomyosarcoma

Abstract: Rare paediatric rhabdomyosarcoma relapse AL Ryan et al.

Cited by 2 publications

References 7 publications

Alveolar rhabdomyosarcoma mimicking acute leukemia in an adolescent with deep venous thrombosis – case presentation

Alveolar rhabdomyosarcoma mimicking acute leukemia in an adolescent with deep venous thrombosis – case presentation

Rabdomiosarcomul alveolar mimând leucemia acută la o adolescentă cu tromboză venoasă profundă – caz clinic

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