Rare nasosinusal tumors: Case series and literature review

Abstract

Tumors of the nasal cavity and paranasal sinuses are unusual pathologies found in clinical practice. Approximately 0.8% of all human cancers are located in this area. Despite being rare, nasosinusal neoplasms usually manifest through nonspecific symptoms that are common to numerous inflammatory pathologies. The aim of this study is to describe a series of rare nasosinusal tumors, including esthesioneuroblastomas, central giant cell granulomas, extramedullary plasmocytomas, nasosinusal hemangiopericytomas, neurofibromas and cemento-ossifying fibromas, diagnosed at the Fortaleza General Hospital. We, hereby, briefly review each of the aforementioned pathologies, stressing the need for a precise histological diagnosis for proper treatment in each case.

Sinonasal extramedullary plasmacytoma: a systematic review of 175 patients

“…All 67 studies included individual patient data that was extractable and fit the minimum criteria for inclusion. The 67 studies are detailed in Table …”

Regression of orbital brown tumor after surgical removal of parathyroid adenoma

“…However, as a result Differential diagnoses for nasosinusal tumors includes: osteoma [most frequent benign tumor of the paranasal sinuses (15)], stesioneuroblastoma, giant cells central granuloma, extramedullary plasmocytoma, angiomatoid lesions (glomangioma and nasosinusal hemangiopericytoma), neurofibroma, cement-ossifying fibroma (13,16,17), osteoblastoma and metastasis (14).…”

“…Tumors in this region usually cause unspecific and common symptoms. Unilateral nasal obstruction, epistaxis, facial pain and local infection are the most common reported initial symptoms (13). Patients with brown tumors in the orbit may have a mass, proptosis, pain, diplopia, decreased extraocular motility or decreased visual acuity (14).…”

Placement of implants in an ossifying fibroma defect obliterated with demineralized, freeze-dried bone allograft and Plasma-rich growth factor

“…In these cases, the tumor may cause facial asymmetry, local pain, teeth loss, root displacement, dental occlusion alterations, cortical thinning, and perforation. [6–8]…”