Rare magnetic resonance imaging findings of intracranial solitary fibrous tumor: A case report

Abstract

Rationale: Solitary fibrous tumor (SFT) is a rare mesenchymal spindle cell tumor. SFT in the central nervous system (CNS) is rare. This case reports rare magnetic resonance imaging (MRI) findings of intracranial SFT (ISFT). Patient concerns: We report a 47-year-old female patient who was found to have weakness in her right limb with walking instability 2 months before the visit. Diagnoses: Based on imaging, the provisional diagnosis was meningioma. Postsurgical histopathological diagnosis confirmed World Health Organization (WHO) grade I SFT/hemangiopericytoma (HPC). Interventions: The lesion was totally excised. The patient improved remarkably after the operation, without any signs of associated limb movement disorder. Outcomes: No local recurrence or metastases were observed in the follow-up 3 months after the surgery. Lessons: Intracranial SFT is a rare mesenchymal tumor. Due to different tumor components, imaging manifestations are diverse and lack of characteristics, so preoperative diagnosis is challenging. Our case provides a rare ISFT with significantly decreased signal intensity in T2 weighted images (T2WI), which is an important supplement to the rare imaging findings of intracranial SFT.

Prevalence of TERT Promoter Mutations in Orbital Solitary Fibrous Tumors

“…However, in our collective, it appeared rather inconsistently. In CNS-related locations, vascularized meningioma shows similar imaging patterns as meningeal SFTs and needs to be considered an important differential diagnosis [47,48]. Interestingly, a recent study by Liu et al demonstrated that DWI imaging (ADC1) could differentiate between SFT and atypical meningioma with high sensitivity and specificity [49].…”

Intracranial Solitary Fibrous Tumor/Hemangiopericytoma: A Series of 14 Cases and Review of the Literature

“…This fusion leads to the pathological and immunohistochemical reversal, manifesting as nuclear STAT6 expression. Consequently, the distinction between the diagnoses of these two tumor types has become increasingly blurred [ 5 ].…”