Rare localizations of bone sarcoidosis: two case reports and review of the literature

Bargagli, Elena; Olivieri, Carmela; Penza, Francesco; Bertelli, Paolo; Gonnelli, Stefano; Volterrani, Luca; Rottoli, Paola

doi:10.1007/s00296-009-1315-7

Cited by 25 publications

(15 citation statements)

References 18 publications

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“…7 Because osseous sarcoidosis is often asymptomatic, this estimation may not reflect the true prevalence. 8 The presence of sarcoidosis in the bones typically correlates with cutaneous lesions and progressive disease. 9,10 In osseous sarcoidosis, bilateral involvement of the phalanges of the hand and feet is most common, 11 but any bone may be affected.…”

Section: Osseous Sarcoidosismentioning

confidence: 99%

Rheumatologic Manifestations of Sarcoidosis

Sweiss

Patterson

Sawaqed

et al. 2010

Semin Respir Crit Care Med

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Sarcoidosis is a systemic, clinically heterogeneous disease characterized by the development of granulomas. Any organ system can be involved, and patients may present with any number of rheumatologic symptoms. There are no U.S. Food and Drug Administration–approved therapies for the treatment of sarcoidosis. Diagnosing sarcoidosis becomes challenging, particularly when its complications cause patients’ symptoms to mimic other conditions, including polymyositis, Sjögren syndrome, or vasculitis. This review presents an overview of the etiology of and biomarkers associated with sarcoidosis. We then provide a detailed description of the rheumatologic manifestations of sarcoidosis and present a treatment algorithm based on current clinical evidence for patients with sarcoid arthritis. The discussion will focus on characteristic findings in patients with sarcoid arthritis, osseous involvement in sarcoidosis, and sarcoid myopathy. Arthritic conditions that sometimes coexist with sarcoidosis are described as well. We present two cases of sarcoidosis with rheumatologic manifestations. Our intent is to encourage a multidisciplinary, translational approach to meet the challenges and difficulties in understanding and treating sarcoidosis.

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Section: Osseous Sarcoidosismentioning

confidence: 99%

Rheumatologic Manifestations of Sarcoidosis

Sweiss

Patterson

Sawaqed

et al. 2010

Semin Respir Crit Care Med

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“…It predominantly affects the small tubular bones of the hands and feet. Exceptional locations at the spine [1], long tubular bones, skull, ribs, and pelvis are also reported [2][3][4]. We report the case of a 52-year-old women in whom systemic sarcoidosis was revealed by bone involvement of the hips.…”

Section: Discussionmentioning

confidence: 98%

Disabling Bilateral Hip Disease and Femoral Bone Defects Revealing Systemic Sarcoidosis

Baccouche¹,

De²,

Bouzaoueche³

et al. 2017

Intern Med

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“…Certain chronic infections such as TB and endemic fungal disease may also lead to similar findings on imaging. CT, magnetic resonance imaging (MRI), and technetium bone scans have high sensitivity for the detection of sarcoid bone lesions, but lack specificity . MRI findings in osseous sarcoidosis usually show low‐signal intensity on T1‐weighted images and high‐signal intensity on T2‐weighted images .…”

Section: Discussionmentioning

confidence: 99%