Rare localization of angiolipoma in the gastrointestinal tract: a case series

Abstract

Objective Angiolipoma is a benign tumor that rarely occurs in the gastrointestinal (GI) tract. This case series was performed to increase clinicians’ understanding of the diagnosis and management of GI angiolipoma. Methods We evaluated the clinical presentations, diagnoses, and treatments of 3 patients with angiolipoma in the upper GI tract in our hospital and 27 cases reported in the literature. Results Among all 30 cases of GI angiolipoma, 2 originated in the esophagus, 4 in the stomach, 2 in the duodenum, 1 in the jejunum, 7 in the ileum, 1 in the cecum, 9 in the colon, 2 in the rectum, and 2 in both the duodenum and colon. Conclusion Angiolipoma of the GI tract may be more likely to occur in middle-aged and elderly men and be located in the ileum and colon. The clinical manifestations generally involve upper GI hemorrhage and lower GI pain and obstruction. Computed tomography and endoscopy may be effective diagnostic techniques, but postoperative histopathologic examination is still the gold standard. The management of angiolipoma in the GI tract depends on the size and type of lesion. Most cases in the present series were managed by complete surgical resection, after which no recurrence was found.

Angiolipoma of the Colon: A Rare Cause of Gastrointestinal Bleeding

“…Moreover, angiolipomas can be distinguished from lipomas by their painful nature, which may be dependent on the degree of vascularity of the tumor [3]. Although many of the colonic angiolipomas in the literature presented with abdominal pain or discomfort, rectal bleeding or positive fecal occult blood testing on examination was more commonly reported on presentation [2,[4][5][6][7][8][9][10][11]. This is consistent with the patient in this case Branching network of thin-and thick-walled vessels vary in sizes.…”

“…This is consistent with the patient in this case report, who initially presented with asymptomatic rectal bleeding for 3 days. Many of the clinical manifestations of colonic angiolipomas appear to correlate with the size of the tumor, and symptoms tend to be nonspecific, making the diagnosis complicated [10].…”

Mesenchymal tumours of the gastrointestinal tract

“…Lipoma subtypes, such as angiolipomas have also been described to occur in the GI tract 60 . Molecularly, benign lipomas harbour simple genetic alteration in about 75% of cases, among which the most common is HMGA2 gene rearrangements 61 .…”

A rare cause of upper gastrointestinal bleeding in an elderly female: Gastric Angiolipoma

“…Although endoscopic and radiologic examination may provide some helpful information, accurate preoperative diagnosis is often challenging. The final diagnosis usually depends on histological examination of the excised specimen, while immunohistochemistry appears to be less specific (3,4). Surgical resection is the main treatment option for gastrointestinal angiolipoma and the recurrence rate is low when the angiolipoma is completely resected (3).…”