Rare Intracardiac Tumor: Primary Cardiac Lymphoma Presenting as Atypical Angina

Aimanan, Karthigesu; Kumar, Kusum; Arif, Mohammad; Zuraini, Noor; Ramdzan, Jamil; Hamdan, Lubna

doi:10.1155/2016/4125295

Cited by 5 publications

(2 citation statements)

References 4 publications

(6 reference statements)

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“…5 Diagnostic modalities include TTE; CT scan; magnetic resonance imaging; positron emission tomography scan; and most conclusively, histopathology of the biopsy. 17 Many cases of cardiac sarcoma involve the right coronary artery. Cardiac catheterization is important to rule out any coronary involvement and determine intervention in case of right coronary artery involvement.…”

Section: Discussionmentioning

confidence: 99%

Near Total Occlusion of Right Ventricle by Cardiac Mass

Mondal

Jubar

Kostibas

2019

Journal of Cardiothoracic and Vascular Anesthesia

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The incidence of primary cardiac tumors is very rare (0.02%) with the majority being benign. Angiosarcoma is the most common malignant cardiac tumor. However, regardless of the histological nature of cardiac tumors, they can cause life-threatening mechanical obstruction. We present a case of urgent surgical removal of a right ventricular (RV) mass. Echocardiography was instrumental for confirmation of the diagnosis, delineation of the anatomical extent of the tumor, evaluation for associated structural involvement and assessment of repair along with constant hemodynamic monitoring.

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Section: Discussionmentioning

confidence: 99%

Near Total Occlusion of Right Ventricle by Cardiac Mass

Mondal

Jubar

Kostibas

2019

Journal of Cardiothoracic and Vascular Anesthesia

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“…PCL is a rare entity that accounts for up to 2% of all primary cardiac tumors. 1,2 The majority of PCLs are B cell malignancies, with diffuse large B-cell lymphoma (DLBCL) being the most common histologic subtype; however, other hematologic neoplasms have been infrequently described. [3][4][5] The clinical presentation of PCL is widely varied, and one third of patients have symptoms of congestive heart failure (CHF).…”

Section: Introductionmentioning

confidence: 99%

Primary cardiac lymphoma A comprehensive review

Zhao,

Zhou

2023

HTIJ

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Objective: To summarize and analyze the clinical features, treatment and prognosis of patients with primary cardiac lymphoma. Method: We herein review the literature available in PubMed databases for recent five years. Then we analyze and summarize the literature data. Result: Among the 26 patients with primary cardiac lymphoma (PCL), the right atrium was most common site involved, and most tumors were single mass, the main symptoms were dyspnoea（65.4%），chest oppression (38.5%) and edema (19.2%). The elevations of lactate dehydrogenase (LDH) were observed, however the bone marrow aspiration or biopsy? Examinations were negative. Atrial fibrillation and atrioventricular block were also noted in some cases. The common expression of immunophenotyping were CD20, Ki-67, multiple myeloma oncogene 1 (MUM1), B-cell lymphoma/leukemia-6 (Bcl-6), CD10, and might be accompanied by expression of Bcl-2, c-myc, CD3 and CD5, while negative expression of CD30, anaplastic lymphoma kinase (ALK), Epstein-Barr virus encoded small RNA (EBER). The majority of patients in this cohort receiving R±CHOP chemotherapy (cyclophosphamide + pirarubicin + vincristine + prednisone with/without rituximab) were reported to have a poor prognosis with 1-year survival rate at 24.1% (9/26). Conclusions: PCL is very rare, with the variable clinical manifestations potentially leading to a delayed diagnosis.

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Fulminant primary cardiac lymphoma with sudden cardiac death: A case report and brief review

Cheng

Lee

Hsu

et al. 2018

Journal of the Formosan Medical Association

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Primary cardiac lymphoma (PCL) is very rare, with the variable clinical manifestations potentially leading to a delayed diagnosis. PCL is usually detected incidentally through image studies, whereas the diagnosis can be confirmed via analysis of pericardial effusion, endomyocardial biopsy tissue, or surgical specimens. Although no standard therapy has been established for PCL, without treatment, the prognosis is grave, with the estimated overall survival being approximately 1 year. We report a difficult diagnosis and complicated case of fulminant PCL, which is the first comprehensively reported case of PCL with secondary hemophagocytosis. A man presented with progressive dyspnea for 3 weeks, and then sudden cardiac death with ventricular fibrillation occurred. After resuscitation, echocardiography revealed a thickened left ventricular wall and severe mitral regurgitation, and computed tomography showed a right atrial mass with diffuse myocardial lesions. PCL was confirmed through a pathological analysis of specimens collected during mitral valvuloplasty, which also implied extensive myocardial involvement. Bone marrow biopsy demonstrated no evidence of lymphoma involvement, but secondary hemophagocytosis was noted. Despite aggressive chemotherapy, the patient died of sepsis with multiorgan failure 26 days after the operation.

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Rare Intracardiac Tumor: Primary Cardiac Lymphoma Presenting as Atypical Angina

Cited by 5 publications

References 4 publications

Near Total Occlusion of Right Ventricle by Cardiac Mass

Near Total Occlusion of Right Ventricle by Cardiac Mass

Primary cardiac lymphoma A comprehensive review

Fulminant primary cardiac lymphoma with sudden cardiac death: A case report and brief review

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