Rare genetic forms of obesity in childhood and adolescence, a comprehensive review of their molecular mechanisms and diagnostic approach

Mainieri, Francesca; La Bella, Saverio; Rinaldi, Marta; Chiarelli, Francesco

doi:10.1007/s00431-023-05159-x

Eur J Pediatr

2023

DOI: 10.1007/s00431-023-05159-x

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Rare genetic forms of obesity in childhood and adolescence, a comprehensive review of their molecular mechanisms and diagnostic approach

Francesca Mainieri,

Saverio La Bella,

Marta Rinaldi

et al.

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2024

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Cited by 2 publications

References 105 publications

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The Genetics of Obesity

Siddiqui,

Kinney,

Han

2024

Pediatric Clinics of North America

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The Genetics of Obesity

Siddiqui,

Kinney,

Han

2024

Pediatric Clinics of North America

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Childhood Obesity and Metabolic Syndrome: A Review

Attina,

Mastrangelo,

Maurizi

et al. 2024

Biomed. Pharmacol. J.

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Obesity is a health condition caused by the accumulation of excess body weight in the form of adipose tissue. This condition has negative effects on a person's overall health. Obesity has a multifactorial etiology involving environmental, genetic, hormonal, and epigenetic factors. The percentage of obese people in childhood is constantly increasing. It is therefore important to implement preventive strategies. This is because Obesity is a systemic condition with major consequences on the endocrine-metabolic, psychosocial, musculoskeletal, respiratory, neurological, gastrointestinal, and especially vascular spheres. Obesity is, in fact, an independent cardiovascular risk factor. Appropriate educational therapy aimed at the child/adolescent and their family is essential. Modifying behaviors that contribute to increased food intake and decreased energy expenditure is essential in promoting healthy lifestyles for individuals and their families.

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Rare genetic forms of obesity in childhood and adolescence, a comprehensive review of their molecular mechanisms and diagnostic approach

Cited by 2 publications

References 105 publications

The Genetics of Obesity

The Genetics of Obesity

Childhood Obesity and Metabolic Syndrome: A Review

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