Rare flavonoids and sesquiterpenoids isolated from the leaves of Goniothalamus gracilipes

Trieu, Quy Hung; Pham, Van Cuong; Retailleau, Pascal; Nguyễn, Văn Hùng; Litaudon, Marc; Doan, Thi Mai Huong

doi:10.1016/j.fitote.2021.105034

Cited by 4 publications

(1 citation statement)

References 29 publications

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“…Different parts of Goniothalamus species have been used for the treatment of fever, scabies, edema, typhoid fever [3], asthma, malaria, stomachache [4], and also as a mosquito repellent [5]. Goniothalamus species produced diverse types of chemical constituents, including styryl lactones [6], alkaloids [3], flavonoids [7,8], steroids, terpenoids [7], and acetogenins [9]. Many of these compounds showed various biological activities such as antimicrobial [10], antioxidant [7], anti-inflammatory [11,12], and cytotoxicity [5,7,9].…”

Section: Introductionmentioning

confidence: 99%

Chemical Composition of the Essential Oils from Goniothalamus tortilipetalus M.R.Hend. and Their Antioxidant and Antibacterial Activities

Anatachodwanit,

Promnart,

Deachathai

et al. 2024

Chemistry

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This work was the first investigation of the essential oil composition of Goniothalamus tortilipetalus M.R.Hend. The aim of this study is to investigate the essential oil composition extracted from different parts of Goniothalamus tortilipetalus M.R.Hend., including flowers, leaves, and twigs, and to evaluate their antioxidant and antibacterial activities. The Clevenger apparatus was used for hydrodistillation to prepare the essential oils. The essential oils were investigated using gas chromatography–mass spectrometry (GC-MS). The three major compounds of the flowers were bicyclogermacrene (15.81%), selin-11-en-4-α-ol (14.68%), and E-caryophyllene (7.02%), whereas the leaves were p-cymene (39.57%), ascaridole (9.39%), and α-copaene (9.12%). In the case of the twigs, α-copaene (10.34%), selin-11-en-4-α-ol (8.85%), and p-cymene (7.76%) were the major compounds. The flower essential oil showed antioxidant activities with IC50 values of 725.21 µg/mL and 123.06 µg/mL for DPPH and ABTS assays, respectively. The flower essential oil also displayed antibacterial activity against Bacillus subtilis, Staphylococcus aureus, Micrococcus luteus, Salmonella typhimurium, and Shigella flexneri, with the same MIC value of 640 µg/mL.

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