Rare cases reports of gastrointestinal stromal tumour (GIST)

Amendolara, M; Ramuscello, S; Broggiato, A; Andreotti, Alessia; Stevanato, Giorgio; Bonfiglio, M; Bernardi, Mauro; Parini, D; Galeotti, F.; Rizzo, Márcia dos Santos

doi:10.11138/gchir/2014.35.5.129

Cited by 4 publications

(9 citation statements)

References 22 publications

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“…Literature search of MEDLINE was performed for all articles in English published from 1998 through 2015. MEDLINE search resulted in 47 case reports 8 9 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 including 57 patients and 6 case series 61 62 63 64 65 66 including 40 cases. As a result, a total of 99 omental GISTs patients were identified.…”

Section: Methodsmentioning

confidence: 99%

Clinicopathological features and prognosis of omental gastrointestinal stromal tumor: evaluation of a pooled case series

Feng

Tian

Liu

et al. 2016

Sci Rep

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Clinicopathological features and prognosis of omental GISTs are limited due to the extremely rare incidence. Therefore, the aim of the present study was to investigate the clinicopathological features and prognosis of omental GISTs. Omental GISTs cases were obtained from our center and from case reports and clinical studies extracted from MEDLINE. Clinicopathological features and survivals were analyzed. A total of 99 cases of omental GISTs were enrolled in the present study. Omental GISTs occurred predominantly in greater omentum (78/99, 78.8%). The majority of tumors exceeded 10 cm in diameter (67/98, 68.3%) and were high risk (88/96, 91.7%). Histological type was correlated with tumor location and mutational status. The five year DFS and DSS was 86.3% and 80.6%, respectively. Mitotic index was risk factor for prognosis of omental GISTs. Prognosis of omental GISTs was worse than that of gastric GISTs by Kaplan-Meier analysis. However, multivariate analysis showed that the prognosis was comparable between the two groups. The majority of omental GISTs were large and high risk. Mitotic index was risk factor for prognosis of omental GISTs. The prognosis was comparable between omental and gastric GISTs.

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Section: Methodsmentioning

confidence: 99%

Clinicopathological features and prognosis of omental gastrointestinal stromal tumor: evaluation of a pooled case series

Feng

Tian

Liu

et al. 2016

Sci Rep

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“…Most reported cases of perforated Meckel’s diverticulum are secondary to foreign body [2, 3] or spontaneous perforation due to diverticulitis [4, 5]. Tumors found in Meckel’s diverticulum are also rare (0.5–3.2 %) [6], with carcinoid being the most common. To date, only 15 cases of GIST arising in a Meckel’s diverticulum have been reported [6–13, 16, 17].…”

Section: Discussionmentioning

confidence: 99%

“…Tumors found in Meckel’s diverticulum are also rare (0.5–3.2 %) [6], with carcinoid being the most common. To date, only 15 cases of GIST arising in a Meckel’s diverticulum have been reported [6–13, 16, 17]. The exact mechanism of perforation in patients with GIST within Meckel’s diverticula has not been fully described in the literature.…”

Section: Discussionmentioning

confidence: 99%

“…Most reported cases of perforated Meckel’s diverticulum are secondary to foreign body [2, 3] and spontaneous inflammation [4, 5]. However, cases exist where tumors such as carcinoid or gastrointestinal stromal tumors (GIST) are found in the resected specimen of perforated or symptomatic Meckel’s diverticulum [6–13]. Perforation in combination with another complication is even more rare [14–16].…”

Section: Introductionmentioning

confidence: 99%

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A gastrointestinal stromal tumor found in perforated Meckel’s diverticulum

Miyata

Bliss

2016

surg case rep

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BackgroundMeckel’s diverticulum is the most common anomaly of the gastrointestinal tract. It is usually asymptomatic, but approximately 4 % present with complications such as bleeding, intestinal obstruction, and inflammation, while perforation is rare. Carcinoid or gastrointestinal stromal tumors are occasionally found in the resected specimens of Meckel’s diverticulum, particularly in the context of perforation.Case presentationA 62-year-old male with a recent history of admission and evaluation for hematochezia presented with abdominal pain. His physical examination was consistent with peritonitis. Results of laboratory testing were significant for white blood cell count of 32,000/μL. CT scan of the abdomen revealed pneumoperitoneum. During the exploratory laparotomy, perforated Meckel’s diverticulum was encountered and segmental bowel resection was performed. Histological examination findings were compatible with gastrointestinal stromal tumor within Meckel’s diverticulum.ConclusionsWhile gastrointestinal stromal tumor is a rare finding in Meckel’s diverticula, the potential for the coexistence of this and other tumors suggests that segmental resection of the small bowel should be considered in the treatment of perforated Meckel’s diverticulum.

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“…Tumours arising from an MD are uncommon, found in 0.5%–3.2%, and are usually incidental. [3] The majority of neoplasms in MD are carcinoid, with few being gastrointestinal stromal tumours (GISTs). [3] Herein, we present a case of a symptomatic GIST arising from an MD that was fully excised laparoscopically.…”

Section: Introductionmentioning

confidence: 99%

Laparoscopic resection of a gastrointestinal stromal tumour in a Meckel's diverticulum

Abdalla

Oke

2019

J Min Access Surg

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A Meckel's diverticulum (MD) is a congenital abnormality of the gastrointestinal tract which is estimated to be present in 2% of the population. Gastrointestinal stromal tumours (GISTs) are rare, soft-tissue tumours which represent 0.1%–3% of all gastrointestinal tumours. The association of an MD and a GIST is extremely unusual since fewer than 3% of MD harbour primary neoplasms and most of these neoplasms are carcinoid tumours. While MDs may remain asymptomatic throughout life, a small proportion may be complicated by occult gastrointestinal bleeding, inflammation, perforation and small bowel obstruction. A tumour in an MD may be asymptomatic or can cause vague abdominal pain and small bowel obstruction if it is larger in dimension. The authors present a rare case of a 5.5 cm GIST in an MD that was completely resected through a laparoscopic approach.

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Rare cases reports of gastrointestinal stromal tumour (GIST)

Cited by 4 publications

References 22 publications

Clinicopathological features and prognosis of omental gastrointestinal stromal tumor: evaluation of a pooled case series

Clinicopathological features and prognosis of omental gastrointestinal stromal tumor: evaluation of a pooled case series

A gastrointestinal stromal tumor found in perforated Meckel’s diverticulum

Laparoscopic resection of a gastrointestinal stromal tumour in a Meckel's diverticulum

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