Rare case of primary hepatoid adenocarcinoma of the lung

Abstract

Hepatoid adenocarcinoma is a rare type of adenocarcinoma with hepatocellular differention, which is characterized by early metastatic spread and poor prognosis. The treatment strategy in not clearly defined due to an extreme rarity of the tumor. Surgery is the most effective tool as a part of multimodality concept. So far, only 51 cases have been described in the literature, and only one in Russia.Clinical case description. We report a case of metastatic hepatoid adenocarcinoma of the lung in a 54-year-old male patient. The difficulties in morphologic differential diagnosis between adenocarcinoma of the lung and primary liver cancer were described. The strategy for managing patients with hepatoid adenocarcinoma of the lung was demonstrated.Conclusion. Hepatoid adenocarcinoma of the lung is a rare tumor with unfavourable outcome.