Rare Case of Endoscopically Diagnosed Ischemic Colitis Secondary to Chronic Phentermine Use
Talwinder Nagi,
Spencer Barnes,
Aaron Weiss
Abstract:Phentermine is an amine anorectic that acts as a sympathomimetic agent and undergoes hepatic metabolism predominantly through CYP3A4. It is commonly used as a mediation to facilitate weight loss. Side effects of phentermine can include pulmonary hypertension, valvular heart disease, palpitations, increased heart rate or blood pressure, diarrhea, and cognitive impairment. Very rarely, phentermine usage has been associated with causing ischemic colitis. The mechanism of action for ischemic colitis from phentermi… Show more
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