Rare Case of a Transverse Colon Schwannoma

Pansari, M.; Lodin, Daud; Gupta, Anupam; Genuit, Thomas; Moseson, Jordan S

doi:10.7759/cureus.7604

Cited by 5 publications

(6 citation statements)

References 17 publications

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“…[ 16 ] The use of radiotherapy and adjuvant chemotherapy have not been advised because of benign behavior presentations. [ 17 18 ] There is a rare incidence of lymph node involvement with loco-regional and liver metastases in aggressive tumors (2%) depending on the large size (more than 5 cm) with multiple mitoses in mitotic index calculation. [ 3 19 ] The patient gave us inform the consent for publication as well.…”

Section: Discussionmentioning

confidence: 99%

Schwannoma of the rectosigmoid colon

et al. 2022

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Section: Discussionmentioning

confidence: 99%

Schwannoma of the rectosigmoid colon

et al. 2022

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“…Normally they are asymptomatic, therefore, the diagnosis is often accidental after an endoscopy. They are usually found in smooth muscle, and by CT, they are homogeneous exophytic tumors that could present cystic changes, necrosis and calcifications (1,(3)(4)(5). The diagnostic challenge is that this is a submucosa lesion, therefore, the endoscopy biopsy is only performed in the mucosa.…”

Section: Discussionmentioning

confidence: 99%

“…Immunohistochemistry can aid the diagnosis if positive for to S-100 and negative for C-KIT, CD-34 or DOG-1 (suggestive findings of GIST tumors), and actin and desmin (leiomyoma diagnostics) (4,5). These immunohistochemistry findings helped in the final diagnosis of the case report here.…”

Section: Discussionmentioning

confidence: 99%

Sigmoid colon Schwannoma simulating colon cancer

et al. 2022

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Schwannomas are tumors of the peripheral nervous system that develop from Schwann cells. They uncommonly develop in the gastrointestinal tract (2-6 %), usually located in the stomach (83 %) and in the small and large intestines in 12 % of cases. Case reportAn 87-year-old female, without any personal background of interest, was studied due to epigastric pain and dyspepsia. A contrast-enhanced computed tomography (CT) scan reported an intraluminal neoplastic process in the sigmoid colon, approximately

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“…Schwannomas are mesenchymal tumors arising from the Schwann cells. They account for approximately 5% of mesenchymal neoplasms [ 7 ]. The stomach is the most frequently encountered site of schwannomas along the gastrointestinal tract, yet it contributes to 0.2% of all diagnosed gastric neoplasms [ 8 ].…”

Section: Discussionmentioning

confidence: 99%

Schwannoma of the Appendix Orifice

Alkhattab

Dhannoon

Sehgal

et al. 2021

Case Reports in Pathology

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Schwannomas are rare mesenchymal tumors. They are usually diagnosed incidentally during endoscopic or diagnostic imaging for another reason. Malignant transformation is rare. In this case report, we present an incidental schwannoma protruding through the appendiceal orifice diagnosed during endoscopy. A healthy 56-year-old female underwent a surveillance colonoscopy for family history of colorectal cancer. A prominent and edematous appendiceal orifice was noted, and the area was aggressively biopsied. Histopathological assessment revealed a benign schwannoma. Computerized topography was unremarkable. Subsequently, the patient underwent a right hemicolectomy. Patient is scheduled to undergo routine surveillance in three years. Grossly, schwannomas are white, encapsulated, and well-circumscribed lesions that stain strongly positive for S100, GFAP, and CD57. Histologically, schwannomas demonstrate spindle cell proliferation. Several imaging modalities have been utilized in the diagnosis and management of mesenchymal neoplasms. Despite the benign nature of the diagnosis, complete surgical resection with clear margins remains the gold standard management strategy. Our case highlights the presence of a relatively uncommon tumor in an unusual anatomical location.

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Rare Case of a Transverse Colon Schwannoma

Cited by 5 publications

References 17 publications

Schwannoma of the rectosigmoid colon

Schwannoma of the rectosigmoid colon

Sigmoid colon Schwannoma simulating colon cancer

Schwannoma of the Appendix Orifice

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