Rare and Challenging Tumor Entity: Phyllodes Tumor of the Prostate

Abstract

Cystic epithelial-stromal tumors of the prostate are rare, with 82 cases reported in literature. These cases have been published under a variety of diagnoses, including phyllodes tumor and prostatic stromal proliferation of uncertain malignant potential as well as a malignant tumor called “prostatic stromal sarcoma”. We report a case of a 60-year-old man with the histological diagnosis of phyllodes tumor of the prostate in transurethral resection specimen.

Benign phyllodes tumour of the prostate: An extremely rare entity

“…There is a great variability in the histological appearance and clinical behaviour of this tumour. 1 Less than 90 cases were reported to date. BPT of the prostate without mitotic activity, as was the case in our patient, is even more rare.…”

“…3 In some cases dedifferentiation, infiltrative growth and extraprostatic invasion can possibly be observed. 1 Histological features are similar to phyllodes tumours of the mammary gland. 1 Cystically dilated ducts with leaf-like stromal projections are typical for phyllodes tumors of both mammary and prostate glands.…”

“…1 Histological features are similar to phyllodes tumours of the mammary gland. 1 Cystically dilated ducts with leaf-like stromal projections are typical for phyllodes tumors of both mammary and prostate glands. 4 An individualized approach to complete resection of the prostate and BPT is required.…”

“…1 Phyllodes tumours, namely epithelial-stromal tumours of the prostate, were first reported in 1960 by Cox and colleagues. 2 Men with BPT of the prostate mostly present with obstructive urinary symptoms and microscopic or macroscopic hematuria.…”

“…4 An individualized approach to complete resection of the prostate and BPT is required. 1 All patients who undergo transurethral resection of the prostate (TURP) as initial surgical treatment should be closely followed for possible recurrence and extraprostatic spread. We report the case of a 59-year-old man with extremely rare benign tumour of the prostate, which was incidentally recognized in flexible cystoscopy.…”