Rare adrenal ganglioneuroma encasing the inferior vena cava

Cai, Tommy Y.; Mendis, Rajith; Das, Kunal; Stephen, Michael S.; Crawford, Michael

doi:10.1111/ans.14744

Cited by 1 publication

(1 citation statement)

References 5 publications

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“…Ko et al[14] and Duffy et al[21] suggested that the presence of fat components in GN may be one of the characteristics of GN, but their sample size was too small to verify this, and we did not notice any fat replacement in our case. Some scholars have proposed that the blood vessels are often surrounded or compressed by GNs instead of being invaded, although most of them are small vessels[16,22], and this finding further suggested that GNs are benign. In this case, GN enclosed all major abdominal vessels, including the celiac trunk, hepatic artery, splenic artery, bilateral renal artery, superior mesenteric artery, inferior vena cava, and portal vein.…”

Section: Discussionmentioning

confidence: 99%

Cause of postprandial vomiting - a giant retroperitoneal ganglioneuroma enclosing large blood vessels: A case report

Zheng¹,

Luo²,

Han³

2019

WJCC

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BACKGROUNDGanglioneuroma (GN) is a rare neurogenic tumor that accounts for about 0.1%-0.5% of all tumors of the nervous system. It originates from neural crest cells. GN has no specific clinical symptoms or laboratory findings, which leaves it easily overlooked and misdiagnosed as other tumors. Retroperitoneal GN with very large volume and vascular penetration is extremely rare.CASE SUMMARYWe present the imaging and pathological findings of a giant retroperitoneal GN in a child. A 4-year-old boy had suffered from postprandial vomiting for more than 6 mo with no precipitating factors. Abdominal computerized tomographic examination showed a giant cystic mass in the retroperitoneal area. After injection of contrast agent, the mass showed heterogeneous enhancement. Surgery with local excision of the mass was performed to address the embedded abdominal blood vessels, and the histopathological and immunohistochemical diagnosis of the mass was GN. Postprandial vomiting was relieved, and no complications occurred after the operation.CONCLUSIONIn the diagnosis of giant retroperitoneal hypodense masses in children, GN should be considered if the mass presents delayed enhancement, punctate calcification, and vascular embedding but no invasion. Pathology is the golden standard for the diagnosis of GN, and surgical excision is the optimal treatment for GN.

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Section: Discussionmentioning

confidence: 99%