Rapidly progressive crescentic IgA glomerulonephritis with glomerular peripheral capillary granular IgA deposits in 6-year old boy

Ushijima, Tadashi; Murayama, H; Hattori, Shinzaburo; Karashima, Shinnyo; Matsuda, Ichiro; Taguchi, Takashi

doi:10.3165/jjpn.8.85

Cited by 3 publications

(1 citation statement)

References 11 publications

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“…Ushijima et al 16 reported a case of rapidly progressive glomerulonephritis in a 6-year-old boy. He showed crescents and IgA deposits along the capillary wall, but not in the mesangium.…”

Section: Discussionmentioning

confidence: 98%

IgA-associated glomerulonephritis with membranoproliferative glomerulonephritis-like pattern in two children

Iitaka

Yamamoto

Ogawa

et al. 2003

Clinical and Experimental Nephrology

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In this article, we report two patients with IgA-associated glomerulonephritis with a membranoproliferative glomerulonephritis (MPGN) -like pattern. Both patients had nephrotic syndrome at onset. One patient was treated with high-dose alternate-day prednisolone (PSL), and the other with indomethacin and low-dose PSL. One lost the urinary abnormalities 3 years after starting treatment. The other lost the nephrotic state and hematuria over a 5-year period, but proteinuria persisted until the last follow-up. Both patients had diffuse proliferative changes with mesangial interposition and subendothelial deposits, associated with strongly positive deposits of C3 and IgA along the capillary walls of the glomeruli. These two patients showed histological changes compatible with type-I MPGN, but the pattern of IgA deposits was not typical of idiopathic MPGN or IgA nephropathy. We assume this is a rare form of MPGN, not associated with liver disease or other systemic diseases.

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“…Ushijima et al 16 reported a case of rapidly progressive glomerulonephritis in a 6-year-old boy. He showed crescents and IgA deposits along the capillary wall, but not in the mesangium.…”

Section: Discussionmentioning

confidence: 98%