Rapidly expanding pigmented lesion of the buccal mucosa

Whitt, J.; Jennings, David R.; Arendt, Douglas M.; Vinton, Jeffrey R.

doi:10.14219/jada.archive.1988.0065

Cited by 14 publications

(14 citation statements)

References 10 publications

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“…Clinically, the lesion appears hyper pigmented black or brown, flat or slightly raised. This lesion, in contrast to most of the benign pigmented lesions discussed above, has a tendency to enlarge rapidly, which raises the possibility of a malignant process in the clinical differential diagnosis [31]. However its tendency to occur in young black females distinguishes it from melanoma, which is uncommon in this age and racial group.…”

Section: Oral Melanoacanthomamentioning

confidence: 88%

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Diagnosis of oral pigmentations and malignant transformations

Tarakji

Umair

Prasad

et al. 2014

Singapore Dental Journal

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Oral pigmentation may present as focal, multifocal or diffused macular or tumefactive lesions. They may greatly vary in color as blue, purple, brown, gray or black depending on the quantity and site of melanin in the tissues [1]. Etiology of pigmentation can be multi factorial. Mostly pigmentation is physiologic but at times it can be a precursor of severe diseases. Lesions may be caused by localized harmless accumulations of melanin, hemosiderin or exogenous metals or they may be a sign of underlying systemic or genetic disease. A few lesions may be associated with life-threatening medical conditions that require immediate intervention. The differential diagnosis for any pigmented lesion is extensive, as it includes examples of endogenous and exogenous pigmentations. Although biopsy is a helpful and necessary aid in the diagnosis of focally pigmented lesions, with diffuse pigmentation lesions require a thorough dental and medical history and laboratory investigations.

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Section: Oral Melanoacanthomamentioning

confidence: 88%

“…Oral melanoacanthoma appears to be a reactive lesion with no malignant potential. In some cases, the lesion disappears after incisional biopsy or removal of the offending stimulus [31].…”

Section: Oral Melanoacanthomamentioning

confidence: 99%

Diagnosis of oral pigmentations and malignant transformations

Tarakji

Umair

Prasad

et al. 2014

Singapore Dental Journal

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“…Hemangioma and mucocele are commonly encountered in oral cavity as pigmented swelling with the color ranging from red to purple. However clinical tests such as diascopy and laboratory investigations such as blood test are useful to reach the definitive diagnosis of hemangioma; on the other hand mucocele is usually associated with a traumatic injury and commonly occurs on the lower lip [8]. Angiofibromas are rare benign mesenchymal tumor characterized clinically by red to purplish swelling and microscopically by bland spindle shaped cells arranged without any pattern in a stroma with wispy collagen and numerous small and medium-sized thick-walled vessels [9].…”

Section: Discussionmentioning

confidence: 99%

“…The former is characterized by blood vessels of different size and smooth muscle content. Immunohistochemical analysis has shown that stromal cells have strong cytoplasmic reactivity for vimentin and are generally immunonegative for smooth muscle actin [8]. …”

Section: Discussionmentioning

confidence: 99%

Pigmented Lesion of Buccal Mucosa

Bajpai¹,

Kumar

et al. 2014

Case Reports in Medicine

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Pigmented lesions are commonly found in the mouth. Such lesions represent a variety of clinical entities, ranging from physiologic changes to manifestation of systemic illness and malignant neoplasm. Diagnosis of such lesions requires a proper case history, extraoral and intraoral examination, and, in some cases, biopsy, aspiration cytology, and laboratory investigations. Here we present a case of purple lesion on the buccal mucosa of a 34-year-old male patient which was provisionally diagnosed as mucocele but on the basis of histopathological picture it was finally diagnosed as angiofibroma, and we also discuss the clinical and histopathological differential diagnosis.

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“…Clinical examination reveals pigmented macules of variable color, ranging in size from 2 to 3 cm. 22,24,27 These authors believe the inflammatory component, the primary pathologic factor in its devel- opment, is responsible for the pigment-filled dendritic cells found in the malpighian layer of the epithelium. 22 Inflammation is a common finding of histologic examination.…”

Section: Discussionmentioning

confidence: 99%